Spectrophotometric Determination of Paracetamol in bulk and Pharmaceutical Preparations

Main Article Content

Rafah K. Ahmed
Saud S. Muhammad
Enaas A. Khodaer

Abstract

A simple, and rapid spectrophotometric method for the estimation of paracetamol has been developed. The methods is based on diazotisation of 2,4-dichloroaniline followed by a coupling reaction with paracetamol in sodium hydroxide medium. All variables affecting the reaction conditions were carefully studied. Beer's law is obeyed in the concentration range of 4-350 ?gml?1 at 490 nm .The method is successfully employed for the determination of paracetamol in pharmaceutical preparations. No interferes observed in the proposed method. Analytical parameters such as accuracy and precision have been established for the method and evaluated statistically to assess the application of the method.

Article Details

How to Cite
1.
Spectrophotometric Determination of Paracetamol in bulk and Pharmaceutical Preparations. Baghdad Sci.J [Internet]. 2015 Jun. 7 [cited 2024 Mar. 29];12(2):317-23. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2072
Section
article

How to Cite

1.
Spectrophotometric Determination of Paracetamol in bulk and Pharmaceutical Preparations. Baghdad Sci.J [Internet]. 2015 Jun. 7 [cited 2024 Mar. 29];12(2):317-23. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2072

Similar Articles

You may also start an advanced similarity search for this article.