Synthesis and Characterization of Some New Benzimidazole Derivatives

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Abdel-Amir M. Fenjan
Sahar T Adday

Abstract

In this paper the new starting material 2-(5-chloro-1H-benzo[d]imidazole-2-yl) aniline (1) was synthesized by the condensation reaction of 4-chloro-o-phenylenediamine and anthranilic acid .The new Mannich base derivatives were synthesized using formaldehyde and different secondary amines to synthesize a new set of benzimidazole derivatives(2-5). Also, the new Schiff-base derivatives (6-10) were synthesized from the reaction of compound (1) with various aromatic aldehydes and the closure-ring was done successfully using mercapto acetic acid to get the new thiazolidine derivatives(11-12).These new compounds were characterized using some physical techniques like:FT-IR Spectra and 1HNMR Spectra.

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Synthesis and Characterization of Some New Benzimidazole Derivatives. Baghdad Sci.J [Internet]. 2016 Mar. 6 [cited 2024 Mar. 28];13(1):0082. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2145
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How to Cite

1.
Synthesis and Characterization of Some New Benzimidazole Derivatives. Baghdad Sci.J [Internet]. 2016 Mar. 6 [cited 2024 Mar. 28];13(1):0082. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2145

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