Levels of Glucose-6-phosphate Dehydrogenase in Type 1 Diabetes Mellitus patients with Nephropathy and Cardiovascular disease complication

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Perry H. Saifullah
Saad M. Nida
Israa B. Raoof

Abstract

The aim of this study is to evaluate oxidative stress in diabetes mellitus (DM) Type1 by the measurement of Glucose-6-phosphate Dehydrogenase (G-6-PD), an enzyme expressed in human RBCs, is important in the generation of reduced glutathione which is the key product in oxidative stress controls. The Study was carried on 80 samples of blood and serum of National Diabetes Center (NDC). The study groups under fasting conditions and they divided as:20 samples of diabetes mellitus patients without complications and 20 samples of diabetes mellitus with cardiovascular (CV) complications and 20 samples of diabetes mellitus with Nephropathy (Neph) complications compared with 20 control group with average age (13-67) years.. The results showed an elevation in the lipid profile and urea levels in patients groups compared with control group and a decrease in glucose-6-phosphate Dehydrogenase, HDL levels in all patients groups compared with control group.

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1.
Levels of Glucose-6-phosphate Dehydrogenase in Type 1 Diabetes Mellitus patients with Nephropathy and Cardiovascular disease complication. Baghdad Sci.J [Internet]. 2014 Jun. 1 [cited 2024 Mar. 29];11(2):461-8. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2651
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How to Cite

1.
Levels of Glucose-6-phosphate Dehydrogenase in Type 1 Diabetes Mellitus patients with Nephropathy and Cardiovascular disease complication. Baghdad Sci.J [Internet]. 2014 Jun. 1 [cited 2024 Mar. 29];11(2):461-8. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2651

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