Synthesis of New Some Imidazole Derivatives Containing ?-Lactam Ring

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Firyal Waly Askar
Rana Abid Ali
Thanaa Mahdi Al-Mouamin

Abstract

In this work 5-methylene-yl - (2-methy –oxazole-4-one) (1H) imidazole (1) were synthesized from the reaction of L-Histidine with acetic anhydride and which converted to the of 5-methylene-yl-(2-methyl 3-amino imidazole-4-one)-1H-imidazole (2) by reaction with hydrazine hydrate. Schiff bases (3-6) were synthesized from the reaction of compound (2) with different aromatic aldehyde. Reaction of compounds (3-6) with chloroacetyl chloride gives azetidinone one derivatives (7-10). These compounds were characterized by FT-IR and some of them with 1H-NMR and 13C-NMR spectroscopy.

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Synthesis of New Some Imidazole Derivatives Containing ?-Lactam Ring. Baghdad Sci.J [Internet]. 2016 Jun. 5 [cited 2024 Mar. 29];13(2.2NCC):0307. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2776
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How to Cite

1.
Synthesis of New Some Imidazole Derivatives Containing ?-Lactam Ring. Baghdad Sci.J [Internet]. 2016 Jun. 5 [cited 2024 Mar. 29];13(2.2NCC):0307. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2776

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