Synthesis of New N-Substituted Phenoxazine Derivatives

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sraa Taha Ibraheem
sraa Taha Ibraheem

Abstract

This work comprises the synthesis of new phenoxazine derivatives containing N-substituted phenoxazine starting from phenoxazine (1). Synthesis of ethyl acetate phenoxazine (2) through the reaction of phenoxazine with ethylchloroacetate, which reacted with hydrazine hydrate to give 10-aceto hydrazide phenoxazine (3), then reacted with formic acid to give 10-[N-formyl acetohydrazide] phenoxazine (4). Reaction of compound (4) with phosphorous pentaoxide or phosphorus pentasulphide to gave 10-[N-methylene-1,3,4-oxadiazole] phenoxazine (5) and 10-[N-methylene-1,3,4-thiadiazole] phenoxazine (6).

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Synthesis of New N-Substituted Phenoxazine Derivatives. Baghdad Sci.J [Internet]. 2016 Jun. 5 [cited 2024 Mar. 29];13(2.2NCC):0360. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2780
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How to Cite

1.
Synthesis of New N-Substituted Phenoxazine Derivatives. Baghdad Sci.J [Internet]. 2016 Jun. 5 [cited 2024 Mar. 29];13(2.2NCC):0360. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2780

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