Synthesis and Study of the Antimicrobial Activity of Modified Polyvinyl Alcohol Films Incorporated with Silver Nanoparticles
Keywords:Antibacterial activities, Modified, Nanocomposites, Poly vinyl alcohol, Silver nanoparticles
A new class of biologically active nanocomposites and modified polymers based on poly (vinyl alcohol) (PVA) with some organic compounds [II, IV, V and VI] were synthesized using silver nanoparticles (Ag-NPs). All compounds were synthesized using nucleophilic substitution interactions and characterized by FTIR, DSC and TGA. The biological activity of the modified polymers was evaluated against: gram (+) (staphylococcus aureus) and gram (-): (Es cherichia coli bacteria). Antimicrobial films are developed based on modified poly (vinyl alcohol) MPVA and Ag-NPs nanoparticles. The nanocomposites and modified polymers showed better antibacterial activities against Escherichia coli (Gram negative) than against Staphylococcus aureus (Gram positive). This work also studied the effect of using different amounts of nanoparticles on the effectiveness against bacteria and it was found that nanocomposite (P2/Ag 5%) has superior antibacterial properties against Escherichia coli.
Published Online First 20/2/2023
Qi W, Zhang X, Wang H. Self-assembled polymer nanocomposites for biomedication. Curr Opin Colloid Interface Sci.2018; 35: 36-41.
Makvandi P, Iftekhar S ,Pizzetti F , Zarepour A, Nazarzadeh E Z, Ashrafizadeh M, et al. Functionalization of polymers and nanomaterials for water treatment, food packaging, textile and biomedical applications: a review. Environ Chem Lett. 2021; 19: 583–611.
Xiumei Li , Wanjia Xu, Yue Xin, Jiawei Yuan, Yuancheng Ji, Shengnan Chu, et al. Supramolecular Polymer Nanocomposites for Biomedical Applications. Polymer. 2021; 13: 513
Kumar Y R, Deshmukh K, Naseer M M, Abhijay G, Al-Onazi W A, Al-Mohaimeed A M, et al. Structure, morphology and modelling studies of polyvinylalcohol nanocomposites reinforced with nickel oxide nanoparticles and grapheme quantum dots. Environ Res. 2022; 203:11842.
Sabaa M W, Abdallah H M, Mohamed N A, Mohamed R R. Synthesis, characterization and application of biodegradable crosslinked carboxymethyl chitosan/poly(vinyl alcohol) clay nanocomposites. Mater Sci Eng. 2015; 56: 363–373.
Awada H, Daneault C. Chemical Modification of Poly (Vinyl Alcohol) in Water. Appl Sci. 2015; 5: 840-850.
Jia Y, Hu C, Shi H, Xu Q, Zhu W, Liu R. Effects of cellulose nanofibrils/graphene oxide hybrid nanofiller in PVA nanocomposites. Int J Biol Macromol. 2020; 161: 223-230.
Li Q, Chen L, Gadinski M R, Zhang Sh, Zhang G, Li H U, et al. Flexible high-temperature dielectric materials from polymer nanocomposites. Nature. 2015; 523:276–580.
Jackson J, Burt H, Lange D, Whang In, Evans R, Plackett D. The Design, Characterization and Antibacterial Activity of Heat and Silver Crosslinked Poly (Vinyl Alcohol) Hydrogel Forming Dressings Containing Silver Nanoparticles. Nanomaterials. 2021; 11 (1): 96.
Lam Sh J, Wong EH H, Boyer C, Qiao G G. Antimicrobial polymeric nanoparticles. Nano Today .2018; 76:40-64.
Ghannam M M, Awad B, Al-Ayed M S, Aly A A. Improving the Physical Properties of Polyvinyl Alcohol (PVA)-Melanin Doping. Egypt J Chem. 2021; 64(7): 3665-3670.
Gomez-Aldapa CA, Velazquez G, Gutierrez M G, Rangel-Vargas E, Castro-Rosas J, Aguirre-Loredo RY. Effect of polyvinyl alcohol on the physicochemical properties of biodegradable starch films. Mater Chem Phys. 2020; 239: 122027
Zhang J, Xu WR, Zhang YC, Han XD, Chen C, Chen A. In situ generated silica reinforced polyvinyl alcohol/liquefied chitin biodegradable films for food packaging. Carbohydr. Polym. 2020; 238: 116182.
Staniszewski Z, Sobolewski P, Piegat A, El Fray M. The effects of nano-sized carbon fillers on the physicochemical, mechanical, and biological properties of polyester nanocomposites. Eur Polym J. 2018; 107(1): 189 201.
Jasso-Gastinel C F, Kenny J M. Modification of Polymer Properties, Elsevier sci. 1th Ed, 2017: 1-206.
Ahangar E G, Abbaspour-Fard M H, Shahtahmassebi N, Khojastehpour M, Maddahi P. Preparation and Characterization of Pva/Zno Nanocomposite. J Food Process Preserv. 2015; 39: 1442–145.
Alesa H J, Aldabbag B M, Salih R N. Natural Pigment –Poly Vinyl Alcohol Nano composites Thin Films for Solar Cell. Baghdad Sci J.2020; 17(3): 832-840
Nasrallah D A, Ibrahim M. A. Enhancement of physico-chemical, optical, dielectric and antimicrobial properties of polyvinyl alcohol/carboxymethyl cellulose blend films by addition of silver doped hydroxyapatite nanoparticles. J Polym Res. 2022; 29(3): 1-20.
Shareef A A , Hassan Z A , Kadhim M A , Al-Mussawi A A. Antibacterial Activity of Silver Nanoparticles Synthesized by Aqueous Extract of Carthamus oxycantha M. Bieb. Against Antibiotics Resistant Bacteria. Baghdad Sci J. 2022; 19(3): 0460-0460.
Alfuraydi R T, Alminderej F M, Mohamed N A. Evaluation of Antimicrobial and Anti-Biofilm Formation Activities of Novel Poly (vinyl alcohol) Hydrogels Reinforced with Crosslinked Chitosan and Silver Nano-Particles. Polymers.2022; 14(8): 1619.
Karam N H, Shanshal A K, Al-Dujail A H. Synthesis, characterization and study of mesomorphic behavior of new bent and linear core compounds containing heterocyclic rings, Mol Cryst Liq Cryst. 2021; 731: 1.
Mustafa R, Othman M B H, Ismail H, Ahmad Z. Synthesis and characterization of rigid aromatic-based epoxy resin. Malaysian J Sci. 2009; 4 (2): 68-75.
Ahmed B J. Synthesis, Characterization and Study of Electrical Properties of Some New Aromatic Polyester. J Glob Pharma Technol. 2018; 10(08): 241-249.
Hajeeassa Kh S, Hussein M A, Anwar Y, Tashkandi N Y, Al-amshany Z M. Nanocomposites containing polyvinyl alcohol and reinforced carbon-based nanofiller: A super effective biologically active Material, Nanobiomedicine. 2018; 5: 1-12.
Garavand Y, Taheri-Garavand A, Garavand F, Shahbazi F, Khodaei D, Cacciotti I. Starch-polyvinyl alcohol-based films reinforced with chitosan nanoparticles: physical, mechanical, structural, thermal and antimicrobial properties. Appl Sci. 2022; 12(3): 1111.
Gaaz T S, Sulong AB, Akhtar M N, Kadhum AA H, Mohamad AB, Al-Amiery A A. Properties and Applications of Polyvinyl Alcohol, Halloysite Nanotubes and Their Nanocomposites, Molecules. 2015; 20: 22833–22847.
Venkatesan R V, Rajeswari N. ZnO/PBAT nanocomposite films: Investigation on the mechanical and biological activity for food packaging. Polym Adv Technol. 2016; 28 (1): 20-27.
Jaramillo A F, Riquelme S A, Sanchez-Sanhueza G, Medina C, Solis-Pomar F, Rojas D , et al. Comparative Study of the Antimicrobial Effect of Nanocomposites and Composite Based on Poly(butylene adipate-coterephthalate) Using Cu and Cu/Cu2O Nanoparticles and CuSO4. Nanoscale Res Lett. 2019; 14: 158.
Guey SH L, Hung Ju yen. Synthesis, Photoluminescence, and Electrochromic Properties of Wholly Aromatic Polyamides Bearing Naphthylamine Chromophores. J Polym Sci A Polym Chem. 2006; 44 (20): 6094-6102.
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