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A Kinetic Study on Microwave- assisted Extraction of Bioactive Compounds from Rosmarinus Officinalis L


  • Eman Al-Mnsour Department of Chemical Engineering, Faculty of Petroleum and Chemical Engineering, Al-Baath University, Homs, Syria.



Extraction, Kinetic, Microwave, models, Rosmarinus officinalis L


Due to the importance of the extraction process in many engineering and medical industries, in addition to great interest in medicinal plants, in this research, microwave-assisted extraction has been applied to extract some active compounds from Rosmarinus officinalis leaves.  The optimal extraction conditions were then determined by calculating the ratio and extraction efficiency. The process has also been described through kinetic study by applying five  kinetic models, the Hyperbolic diffusion model,  Power low model, the First order reaction  model, Elovich's model, and Fick's second law diffusion model and determining their compatibility with the studies operation, and determining the kinetic constants for each model. The results of extracts showed that the best conditions are: the solvent is ethyl alcohol 80%, the capacity is 720W, and time is 6.5 min. For the kinetic study, all the studied models were appropriate to the applied extraction tip with high correlation coefficients, therefore, the kinetic constants of all these models were determined.


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Kodi M., Hassan M , Nader M. Effect of alcohol olic Extracts of Rosmarinus officinalis and Propolis on inhibition of Staphylococcus aureus and Klebsiella pneumoniae biofilm isolate from urinary tract infection. JUAPS. 2018; 12(1). http//

Wang Y, Wang S, Yang D, Chen Y, Fu S, Samuel. Effects of natural antioxidant, polyphenol- rich rosemary extract, on lipid stability of plant- derived omega-3 fatty- acid rich oil. LWT. 2018; 89: 210-216.

Sulaiman M, Tayeb T. Response of broiler Chicken to inovo administration of different levels of Rosemary oil (rosmarinus officinalis). Iraqi J Agric Sci. 2021; 52(4):896-903.

Haidar A, Douha A. Study of some chemical properties of Rosemurinus officinalis L., and evaluation of the inhibitory effect of its alcohol extract in some pathogenic bacteria. UTJagr . 2018; 1(7). http//jam.

Andrad A, Santos R, Bonito M, Saraiva M, Sikva A. Characterrization og rosemary and thyme extracts for incorporation into a whey protein based film. LWT.2018; 92: 497-508.

Micic D, Durovic S, Riabov P, Tomic A, Tosti T, Dojcinovic B, Javanovic D, Blagojevic S, Rosemary essential oils as promising source of compounds: chemical composition, thermal properties, biological activity, and Gastronomical prespectives. Foods. 2021; 10(11): 2734.

Shakir k, Rasheed H, Ahmed E. Study of Rosemary Essential Oil Antibacterial Effect on bacteria Isolated from Urinary Tract Infections in some Hospitals of Baghdad. Curr Res Microbiol Biotechnol. 2018, 6(1): 1490-1495

Mezza G, Borgarello A. Grosso N, Frenandes H, Pramparo M, Gayol M. Antioxidant activity of rosemary essential oil fractions obtaind by molecular distillation and their effect on oxidative stability of sunflower oil. Food Chem. 2018; 242: 9-15.

Zainab M, Abdul Husain1, Lamiya K. Effect of some growth regulators on the multiplication and stimulating the production of the volatile oil of Rosemary Officinalis invitro. Plant Archives . 2019; 19(1):1773-1782.

Navarro M, Rombaut N, Fabiano A, Danguien M, Bily A. Ultrasound versus microwave as green processes for extraction of rosmarinic, carnosic and ursolic acids from rosemary. Ultrason Sonochem. 2015; 27:.102-109.

Zhitong Y, Shaoqi Y, Weiping S, Weihong W, Junhong T, Wei Q. Kinetic studies on the pyrolysis of plastic waste using a combination of model- fitting anf model- free method. Waste Manag Res.2020; 38(1): 77-85. -access-at-sag.

Koturevic B, Adnadjevic B, Jovanovic J. The kinetics of the extraction of caffeine from guarana seed under the action of ultrasonic field with simultaneous cooling. Green Process Synth .2020; 9: 26–36.

Shewale S, Rathod VK . Extraction of total phenolic content from Azadirachta indica or (neem) leaves: Kinetics study. Prep Biochem Biotechnol .2018 ; 48(4): 312–320.

Haqqyana H, Mardinah A, Kusuma H, Altway A, Mahfud M. Kinitic study in the extraction of essential oil from Clove stem using microwave hydrqdistillation. Mor J Chem .2020; 8(1): 064-071 http//

Hassan A, green synthesis of Iron/Copper nanoparticles as catalysts in Fenton – like reactions for the purpose of removing the orange dye G. Baghdad Sci J. 2022; 19(6): 1249-1265.

Mahmod S. Adsorption of some aliphatic Dicarboxlic acid on Zinc Oxide Kinetic and Thermodynamic study. Baghdad Sci J. 2019; 16(4): 892-898.

Balyan U, Sarkar B . Aqueous extraction kinetics of phenolic compounds from jamun (Syzygium cumini L.) seeds. Int J Food Prop .2016; 20(2): 372–389.

Hobbi P, Valentine O, Delporte C, Alimoradi H, Podstawczyk D, Nie L, Katrien V. Bernaerts and Amin Shavandi1. Kinetic modelling of the solid–liquid extraction process of polyphenolic compounds from apple pomace: influence of solvent composition and temperature. Bioresour. Bioprocess. 2021; 8: 114.

Tao Y, Zhang Z, Sun D.W. Kinetic modeling of ultrasound-assisted extraction of phenolic compounds from grape marc: Influence of acoustic energy density and temperature. Ultrason Sonochem. 2014; 21(4): 1461-1469.

Galgano F, Tolve R, Scapa T., Condelli N. Extraction Kinetics of Total Polyphenols, Flavonoids,and Condensed Tannins of Lentil Seed Coat: Comparison of Solvent and Extraction Methods. Foods. 2021; 10(8): 1810. .

Kashaninejad M, Sanz M, Blanco B, Beltrán S, Niknam S. Freeze dried extract from olive leaves: Valorisation, extraction kinetics and extract characterization. Food bioprod. Process. 2020; 124: 196–207.

Tomšik A, Pavlic B, Vladic J, Ramic M, Brindza J, Vidovic S. Optimization of ultrasound-assisted extraction of bioactive compounds from wild garlic (Allium ursinum L.). Ultrason Sonochem. 2016; 29: 502–511.

Pradal D, Vauchel P, Decossin S, Dhulster P, Dimitrov K. Kinetics of ultrasound-assisted extraction of antioxidant polyphenols from food by-products: Extraction and energy consumption optimization. Ultrason Sonochem .2016; 32: 137–146.

Kitanovi´c S, Milenovi´c D, Veljkovi´c V.. Empirical kinetic models for the resinoid extraction from aerial parts of St. John’s wort (Hypericum perforatum L.). Biochem Eng J .2008; 41: 1–11.

Lafka T, Lazou A E, Sinanoglou V J, Lazos E S. Phenolic Extracts from Wild Olive Leaves and Their Potential as Edible Oils Antioxidants. Foods. 2013; 2: 18–31.