New Method for Estimation Mebeverine Hydrochloride Drugs Preparation by a New Analyser: Ayah 6S.X1(WSLEDs)-T.- Two Solar Cells Complied with C.F.I.A

Main Article Content

Omar A. Yassin
Nagam S.Turkey Al Awadie

Abstract

A sensitivity-turbidimetric method at (0-180o) was used for detn. of mebeverine in drugs by two solar cell and six source with C.F.I.A... The method was based on the formation of ion pair for the pinkish banana color precipitate by the reaction of Mebeverine hydrochloride with Phosphotungstic acid. Turbidity was measured via the reflection of incident light that collides on the surface particles of precipitated at 0-180o. All variables were optimized. The linearity ranged of Mebeverine hydrochloride was 0.05-12.5mmol.L-1, the L.D. (S/N= 3) (3SB) was 521.92 ng/sample depending on dilution for the minimum concentration, with correlation coefficient r = 0.9966while was R.S.D% < 1% of 2, 6 mmol.L-1 conc. of Mebeverine hydrochloride. The method is used successfully for three different of target drugs in three different pharmaceutical formulations. A comparison using t-test was studied. It was shown that there is no significant difference between two values.

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New Method for Estimation Mebeverine Hydrochloride Drugs Preparation by a New Analyser: Ayah 6S.X1(WSLEDs)-T.- Two Solar Cells Complied with C.F.I.A . Baghdad Sci.J [Internet]. 2021 Sep. 1 [cited 2024 Mar. 29];18(3):0565. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/4662
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How to Cite

1.
New Method for Estimation Mebeverine Hydrochloride Drugs Preparation by a New Analyser: Ayah 6S.X1(WSLEDs)-T.- Two Solar Cells Complied with C.F.I.A . Baghdad Sci.J [Internet]. 2021 Sep. 1 [cited 2024 Mar. 29];18(3):0565. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/4662

References

Brunton, LL, Lazo JS, Parker KL. The Pharmacological Basis of Therapeutics. 11th ed. USA;2005.2047p

Matthieu T, Carlos A R. Flow injection visible diffuse reflectance quantitative analysis of total sulfur in biodiesel, in plant leaves and in natural waters . Ecl. Quím., São Paulo. 2009; 34(2): 29 – 36.

Krug FJ, Bergamin Filho H, Zagatto EA, Jørgensen SS. Rapid determination of sulphate in natural waters and plant digests by continuous flow injection turbidimetry. Analyst.1977;102: 503-508.

Nagam S, Rana A. CFIA- Turbidimetric and Photometric Determination of vitamin B2 using LEDs as a source of irradiation and two solar cells as an energy transducer. IJSR. 2017. May; 6 : 1832-1844

Nagam S, Rana A. CFIA- Turbidimetric and photometric determination of vitamin B9 (folic acid)using LEDs as a source of irradiation and two solar cells as an energy transducer. BSJ. 2017 Dec;14(4):773-786

Nagam S, Mustafa K. Determination of Mefenamic Acid Using a New Mode of Irradiation (Array of Six Identical LEDs) and Detection( Twin Solar Cells) Through Turbidity Measurement by CFIA. I. J. S. 2016 Jun; 57:1052-1070

Souri E, Negahban A, Adib N. A stability indicating HPLC method for determination of mebeverine in the presence of its degradation products and kinetic study of its degradation in oxidative condition. Res Pharm Sci. 2014 Jun; 9(3):199-206.

Ramadevi S, Srikanth A, Ashok K. RP HPLC method development and validation for simultations quantitative estimation of mebeverine hydrochloride and chlordiazepoxide in capsules. Int J Pharm Pharm Sci.2015Oct; 7(2) : 314-318

Jagadeesh C S, Senthilkumar G P, Chandan R. Method development and validation of mebeverine HCL in bulk druges by RP-HPLC method .WJPPS. 2017 March; 6(4): 1543-1551

Dhanapal Y, Senith S K. Analytical Method Development and Stability Indicating an RP-HPLC Method for Determination of Mebeverine HCl and Chlordiazepoxide. IJPPR. 2018 April;12(1):307-326

Sujana K, Hamuthal MZV, Murthy VSN, Shravani N. A Novel Validated Analytical Method Development for the Binary Mixture of Mebeverine and Chlordiazepoxide in Pharmaceutical Formulation and its Application to Stress Studies. Pharm Anal Acta. 2015 Dec;6(1).1-6

Othman AA, Bagary RI, Elkady EF, El-Kerdawy MM. Development and Validation of Spectrophotometric Methods for Simultaneous Determination of Mebeverine Hydrochloride and Chlordiazepoxide In Bulk and In Dosage Form.Pharm Anal Acta.2016 July; 7(8).1-8

Naveed S, Waheed N, Nazeer S, Rehman H. Method Development of Mebeverine Hydrochloride by Using UV Spectrophotometric Method. IJAS.2015 Jan; 2:001-005

Abdulbari M, Zainab A. Spectrophotometric Determination of Mebeverine hydrochloride in pharmaceutical preparation via Ion Association Reaction. J. Phys.2018May;1032:1-9

Nagam S , Omar A. New Approach for the On-Line Spectrophotometric Determination of Vanadium (V) In Different River Water via the Use of a Homemade Ayah 6SX1-T-2D Solar-Continuous Flow Injection Analyser. IJS. 2014Dec; 55(4B):1721-1735

Miler JC, Miller JN. Statistics for Analytical Chemistry. 2nd ed. England; 1988. 227 p

Bluman AG. Elementary Statistics.3rd ed. Ed. New York;1997. 657p

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