Abstract
A simple, rapid and sensitive spectrophotometric method has been developed for the determination of captopril in aqueous solution. The method is based on reaction of captopril with 2,3-dichloro 1,4- naphthoquinon(Dichlone) in neutral medium to form a stable yellow colored product which shows maximum absorption at 347 nm with molar absorptivity of 5.6 ×103 L.mole-1. cm-1. The proposed method is applied successfully for determination of captopril in commercial pharmaceutical tablets.
Article Type
Article
How to Cite this Article
Mohammed, Dawood H.; Shehab, Intesar A.; and Ahmed, Hend
(2013)
"Spectrophotometric method for the determination of Captopril in pharmaceutical formulations,"
Baghdad Science Journal: Vol. 10:
Iss.
3, Article 41.
DOI: https://doi.org/10.21123/bsj.2013.10.3.965-970