Abstract
The present work involved synthesis of several new N-Sulfamethoxazol derivatives imide on Polymeric chain by two steps. The first stip involved preparation of N- (sub.orunsub benzoyl and sub unsub acetyl) amidyl sub sulfamethoxazole (1-5) by condensation of sulfamethoxazole drug with many substituted acid chloride, then the second step include, preparation new five N-(acrly-N–sub or unsub benzoyl) imidyl substituted sulfamethoxazol(6-10) by reaction of poly acryloyl chloride with the prepared compound (1-5) in first stepin asuitable solvent in the presenceamount triethylamine (Et3N) with heating. The structure confirmations of all polymers wereconfirmed using FT-IR,1H-NMR,13C-NMR and UV spectroscopy. Other physical properties including softeningpoint's, melting point, and solubility of the polymers were also measured.
Keywords
Sulfamethoxzole drug, poly acryloyl chloride, polyamides derivatives.
Article Type
Article
How to Cite this Article
Al-Bayati, Sameaa J. Khammas; Sadiq, Amal S.; and Mahmood, Tamador A.
(2014)
"Synthesis of N –sulfamethoxazolederivative imide on polymeric chain,"
Baghdad Science Journal: Vol. 11:
Iss.
4, Article 18.
DOI: https://doi.org/10.21123/bsj.2014.11.4.1567-1576
