Abstract
Type 1 diabetes mellitus (T1DM) is an autoimmune disease frequently associated with autoimmune thyroid disease (AITD). The study was conducted at the Specialized Center for Endocrinology and Diabetes-Baghdad at Al-Karkh side, from December 2013 to April 2014. In this study, we investigate the prevalence of anti-thyroid peroxidase (anti-TPO) antibody in 80 type 1 diabetic patients with AITD and 30 healthy controls. Blood samples were taken for thyroid tests using the Vitek Immunodiagnostic Assay System (VIDAS). Enzyme Linked Immunosorbent Assay (ELISA) was used to detect anti-thyroid antibody (anti-TPO). The results show that age, gender, and BMI (body mass index) are similar in both groups (p>0.05). Among 80 type 1 diabetic patients, 15 (18.8%) are positive. There is a highly significant difference (p<0.01) between TSH (Thyroid Stimulating Hormone) levels and the frequency of positive and negative anti-TPO, while there is a non-significant difference (p>0.05) between T3 & T4 levels and the frequency of positive and negative anti-TPO.
Keywords
BMI, FBS, T3, T4, TSH, Anti-TPO
Article Type
Article
How to Cite this Article
Jabar, Sara S.; Mohammed, Sanad B.; and Mahdi, Abass R.
(2016)
"Level and Statistical Distribution of Thyroid Peroxidase and Thyroid Hormones in Iraqi patients with Type1 Diabetes Mellitus at Al-Karkh Side,"
Baghdad Science Journal: Vol. 13:
Iss.
2, Article 15.
DOI: https://doi.org/10.21123/bsj.2016.13.2.0312
