Synthesis of New N-Substituted Phenoxazine Derivatives

Authors

Israa Taha Ibraheem, Department of Chemistry, College of Science, University of Baghdad, Baghdad, Iraq.Follow
Suad M. Al.Araji, Department of Chemistry, College of Science, University of Baghdad, Baghdad, Iraq.

Abstract

This work comprises the synthesis of new phenoxazine derivatives containing N-substituted phenoxazine starting from phenoxazine (1). Synthesis of ethyl acetate phenoxazine (2) through the reaction of phenoxazine with ethylchloroacetate, which reacted with hydrazine hydrate to give 10-aceto hydrazide phenoxazine (3), then reacted with formic acid to give 10-[N-formyl acetohydrazide] phenoxazine (4). Reaction of compound (4) with phosphorous pentaoxide or phosphorus pentasulphide to gave 10-[N-methylene-1,3,4-oxadiazole] phenoxazine (5) and 10-[N-methylene-1,3,4-thiadiazole] phenoxazine (6).

Keywords

phenoxazine, ethyl acetate phenoxazine, 10-aceto hydrazide phenoxazine

Article Type

Supplemental Issue

How to Cite this Article

Ibraheem, Israa Taha and Al.Araji, Suad M. (2016) "Synthesis of New N-Substituted Phenoxazine Derivatives," Baghdad Science Journal: Vol. 13: Iss. 2, Article 61.
DOI: https://doi.org/10.21123/bsj.2016.13.2.2NCC.0360