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Abstract

Hypertension is one of the leading causes of the global burden of disease, which causesserious health problems. The aim of this study isto investigate the lipid profile levels in sera of Iraqi hypertensive patients by measuring Total cholesterol (TC), triglyceride (TG) and low density lipoproteins (LDL) and kidney function levels by measuring uric acid, urea and creatinine. Seventy five individuals of Iraqi adults (Males) were divided into three groups:25 hypertensive patients with duration of disease (1-10) year (group 1), 25 hypertensive patients with duration of disease (11-30) year (group 2) and 25 normal individuals as control group (group3). The findings indicate that serum (TC, TG and LDL) levels were significantly elevated (p ≤ 0.05) comparedwith healthy group and the values of them were significantly higher in group 2 thaningroup 1.This studyalso shows significant positive correlations between TC and TG, LDL (p ≤0.01),(p ≤ 0.05)respectively.Fromcollected data, a significant increasewas foundin the mean value of serum uric acid,urea and creatinine in hypertensive patients in two groups(1,2) comparedwith control group and the levels of them were significantly higher in group2 thaningroup1 (p≤0.01).The results also indicate strong correlations between parameters studied of kidney function tests (p≤ 0.01). This study hasshown thatlipid profile and renal function levels abnormalities are highly prevalent among Iraqi hypertensive patients and alsothe effect of duration of disease on parameters wasstudied.

Keywords

Hypertension, lipid profile, Renal function tests

Article Type

Article

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