Characterization and Biological Activity of Some New Derivatives Derived from Sulfamethoxazole Compound

Authors

sanaa A. alsahib, Department of Chemistry, College of Science for Woman, University of Baghdad, Baghdad, IraqFollow

Abstract

A new series of Sulfamethoxazole derivatives was prepared and examined for antifibrinolytic and antimicrobial activities. Sulfamethoxazole derivatives bear heterocyclic moieties such as 1,3,4-thiadiazine {3}, pyrazolidine-3,5-diol {4} 6-hydroxy-1,3,4-thiadiazinane-2-thione {5} and [(3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-4-yl)diazenyl] {8}. Their structures were elucidated by spectral methods (FT-IR, H1-NMR). Physical properties are also determined for all compound derivatives. Recently prepared compounds were tested for their antimicrobial activity in the laboratory. Each screened compound showed good tendency to moderate antimicrobial activity.

Keywords

Biological activity, Characterization, Sulfamethoxazole, Synthesis.

Article Type

Article

How to Cite this Article

alsahib, sanaa A. (2020) "Characterization and Biological Activity of Some New Derivatives Derived from Sulfamethoxazole Compound," Baghdad Science Journal: Vol. 17: Iss. 2, Article 10.
DOI: https://doi.org/10.21123/bsj.2020.17.2.0471