Preparation, Diagnosis, Theoretical Study, Biological Evaluation and Antioxidant Assay of ZrO₂ Oxide Nanoparticles Using Environmentally Friendly Method

Authors

Wafaa Fayyad Tharp, Departments of Chemistry, College of Education for Pure Sciences, Ibn Al-Haitham, University of Baghdad, IraqFollow
Lekaa K. Abdul Karem, Departments of Chemistry, College of Education for Pure Sciences, Ibn Al-Haitham, University of Baghdad, IraqFollow

Abstract

This research included using an environmentally friendly method to synthesize nano particles of zirconium oxide using chamomile plant extract as a reducing agent in basic medium at pH 12, and then preparing the metal oxide using various techniques such as FTIR spectroscopy, scanning and transmission electron microscopy (SEM and TEM), energy-dispersive X-ray spectroscopy (EDX) to calculate the percentages of elements. The infrared spectrum showed the appearance of spectral bands at 559 and 441 cm^–1 due to the formation of the bond between the oxygen and zirconium. Depending on AFM analysis, the average mean size of ZrO₂ Nano partials was 45.11 nm, the measurement of crystal size in nanoparticles was conducted using Debye Scherer’s equation in x-ray diffraction, resulting in a value of 7.59 nm. XRD showed that the ZrO₂ nanoparticles had a tetragonal crystal structure. The zirconium oxide was also studied theoretically using the Hyper Chem-8.0.7 program, where Vibration frequencies of t-zirconium dioxide were calculated at 567 cm^–1, which matches the practical value, draws the tetragonal geometry optimization. Antimicrobial activities of ZrO₂ nanoparticles have been studied against Bacillus, Klebsiella and Candida fungus in different concentrations of (25%, 50%, and 100%) in DMSO solvent medium, ZrO₂ nanoparticles showed different efficacy towards these antimicrobial. The DPPH radical scavenging activity in different concentrations (12.5, 25, 50, 100, and 200 ppm) were used to analyze the antioxidant scavenging activity of ZrO₂ nanoparticles, the potential antioxidant activity of ZrO₂ NPs could be useful as anticancer agents and other deleterious diseases in future.

Keywords

Antioxidant, Environmentally friendly, Green synthesis, Plant extract, Theoretical study

Subject Area

Chemistry

Article Type

Article

First Page

17899

Last Page

17908

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite this Article

Tharp, Wafaa Fayyad and Karem, Lekaa K. Abdul (2025) "Preparation, Diagnosis, Theoretical Study, Biological Evaluation and Antioxidant Assay of ZrO₂ Oxide Nanoparticles Using Environmentally Friendly Method," Baghdad Science Journal: Vol. 22: Iss. 11, Article 5.
DOI: https://doi.org/10.21123/2411-7986.5107