Synthesis and Characterization of New Acrylamide Derivatives and Studying Their Antibacterial Activity

Authors

Ruaa M. Dhedan, Department of Chemistry, College of Science for Women, University of Baghdad, Baghdad, IraqFollow
Sana H. Awaad, Department of Chemistry, College of Science for Women, University of Baghdad, Baghdad, IraqFollow
Suha. N. Fadhl, Department of Chemistry, College of Science for Women, University of Baghdad, Baghdad, IraqFollow

Abstract

This study aims to test the new derivatives of polymers on the biological activities of two types of bacteria work describes the synthesis of 1,3-oxazepine and self-polymerization via a cycloaddition reaction between Schiff's bases 2-methyl-N-(5-(2-methylbutanoylimino) pentylidene)but-2-enamide and succinic, maleic anhydride. The synthesized compounds were characterized by melting points, softening points, and physical properties such as swelling capacity, TGA, and FT-IR. The biological activity showed intermediate results against two bacterial isolates resistant to antibiotics.

Keywords

Acrylamide, Antibacterial activity, Heterocyclic compounds, Oxazepine, Schiff s bases

Article Type

Article

First Page

361

Last Page

370

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite this Article

Dhedan, Ruaa M.; Awaad, Sana H.; and Fadhl, Suha. N. (2025) "Synthesis and Characterization of New Acrylamide Derivatives and Studying Their Antibacterial Activity," Baghdad Science Journal: Vol. 22: Iss. 2, Article 1.
DOI: https://doi.org/10.21123/bsj.2024.8556