•  
  •  
 

Abstract

A new type of electrodes was prepared for determination of drugs depended on (TCH- PM-CuO NPs). This work recommended a novel CuO nanoparticles-depended on coated wire sensors for detected tetracycline hydrochloride (TCH) in pure and pharmaceutical formulations. Tetracycline, hydrochloride, and molybdophosphoric acid (PM) were combined in the finding of polymeric poly vinyl chloride (PVC) and o -nitro phenyl octyl ether (o -NPOE) as a solvent mediator to formula an electro-active material is tetracycline- molybdophosphoric acid (TCH-PM). The adapted sensors utilizing TCH-PM-CuO nanoparticles showed high selectivity and sensitivity for the quantification and discrimination of TCH with a linear range 1.0 × 10-9-1.0 × 10-2 mol L-1 and detection limit of 3.0×10-10, 2.5×10-10 and 1.5×10-10 mol.L-1 for TCH-PM-CuO NPs, TCH-PM-CuO NPs with leaves extract of Myrtus communis and TCH-PMA-CuO NPs with leaves extract of Mentha coated wire electrodes. The proposed electrodes were used for the determination of TCH in pure form, pharmaceutical formulation, respectively.

Keywords

Coated wire electrodes, CuO Nanoparticles, Ion-pair, Leaves extract, Tetracycline

Subject Area

Chemistry

Article Type

Article

First Page

2193

Last Page

2202

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Download

Share

COinS