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Abstract

The reaction between triethylorthoformate and p-chlorophenyl resulted in formation of N,N'-bis-(p-chlorophenyl)formamidine ligand. Subsequently, this ligand interacted with the following metal ions (Co+2, Ni+2, Cu+2, Cr+3 and Ru+3) creating air-stable complexes with formula [M(L)2(H2O)n(Cl)x](X= 0, 1) with distinct octahedral morphologies. The formation of these compounds was identified using mass spectroscopy (MS), which validated the acquired geometries. Fourier transform infrared (FT-IR) spectroscopy analysis demonstrated how the formamidine group formed and how it coordinated with the metal ions. Studies using pyrolysis (Thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC)) verified that water residues could be coordinated with metal complexes. Additionally, elemental micro-analysis (CHN), ultraviolet-visible (UV-Vis) spectroscopy, conductivity and melting points examination were performed. Proton nuclear magnetic resonance (1H-NMR) and magnetic susceptibility (χm) can also reveal the existence of the coordination with the metals and the ligand (HL) formation. The prepared ligand and its synthesized metal complexes were screened for their biological activity against bacterial species, one of Gram-positive bacteria and the other was Gram negative bacteria, as well as fungi assessment. The compounds' antioxidant records were finally evaluated using ((2,2-diphenyl-1-picrylhydrazyl) (DPPH)) method. It was determined that gallic acid, as a standard substance, has a IC50 value. These complexes have the ability to be used as scavenging free radicals DPPH.

Keywords

Antioxidant determination, Biological activity, N, N'-bis-(p-chlorophenyl) formamidine ligand, Mass spectroscopy, Metal complexes.

Subject Area

Chemistry

Article Type

Article

First Page

2214

Last Page

2229

Creative Commons License

Creative Commons Attribution 4.0 International License
This work is licensed under a Creative Commons Attribution 4.0 International License.

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