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Abstract

The effect of the crude alcoholic extract of the fenugreek seeds, given. orally to albino male mice, on the physiological and histological changes of the testes was studied. The extract was give daily in different concentrations (0.25, 1.25, and 2.5 mg/ml) for 35 days. The histology of the testes revealed cells of varying degrees of desquamation and degeneration in the epithelial cells of of the seminiferous tubules. Vacules were also noticed within the epithelial cells of both seminiferous tubules and epididymal tubes. A significant decline was found in number of sperm produced. No significant differences were scen in the diameter. the seminiferous and epididymal tubules. The effect on the epithelial height of the epididymal tubes was also not significant. It could be concluded that the crude alcoholic extract of the fenugreek seeds may have a negative effect on the fertility of the albino male mice.

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