Abstract
200 urine specimens were collected from patients with urinary tract infection and speculated for Klebsiella specics. 70 specimens (35%) showed growth and 11 isolates (15.7%) were identified as Klebsiella species (K. pneumoniae, K. oxytoca and K. Most of local isolates revealed high resistance to antibiotics: Penicillin G. Ampicillin, Amoxicillin, Piperacillin, Cephalothin, Cefaclor and Cefotaxime. moderate resistance to cephalexin, Ceftazidime and Cefixim and low resistance to Augmentin, Cefoxitin an Ceftizoxime. The MICs of Amoxicillin, Piperacillin, Cephalexin and Cephalothin (512-1024) µg/ml were higher than other antibiotics (32-512) µg/ml and 10 isolates (90.9%) produced B-lactamase. The cations Mg2+ and Cat were more affective in decreasing the ceftizoxime MICs than other cations. No significance effect of Fe³ and Zn² on MICs in all concenentrations (1, 2.5, 5, 10) µg/ml while Na caused increasing in MICs at concentrations (0.5, 1)%.
Article Type
Article
How to Cite this Article
Ghanima, Kais K.
(2006)
"Development of resistance of some Klebsiella species isolated locally from urinary tract infection to some beta - lactam antibiotics,"
Baghdad Science Journal: Vol. 3:
Iss.
4, Article 19.
DOI: https://doi.org/10.21123/bsj.2006.755
