Abstract
The pathogenicity of S. saprophyticus was studied in mice. A group of white mice were injected transurethrally using a catheter with S. saprophyticus S67 cell suspension in a concentration reached 109 CFU/ml. concomitantly, the role of its peptidoglycan in the pathogenicity was studied by injecting another group of mice with 0.3 mg/0.2 ml of partially purified S. saprophyticus S67 peptidoglycan extract. After autopsy, kidneys and urinary bladder showed several histopathological changes both in cells and peptidoglycan injected mice, included: hydropic degeneration, glomerulus shrinkage, congestion of renal vessels, infiltration of inflammatory cells, and dekeratinization in urinary bladder.
Article Type
Article
How to Cite this Article
Al-Mathkhury, Harith J.F.; Flaih, May T.; and Fleih, Athra S.
(2007)
"Role of peptidoglycan in the pathogenesis of Staphylococcus saprophyticus in mice,"
Baghdad Science Journal: Vol. 4:
Iss.
4, Article 10.
DOI: https://doi.org/10.21123/bsj.2007.4.4.597-602
