Abstract
Adenosine deaminase (ADA; Ec: 3.5.4.4), 5 ́-Nucleotidase(5 ́–NT; Ec: 3.1.3.5), and AMP –amino hydrolase (AMP –deaminase AMPDA; Ec: 3.5.4.6) activities were measured in sera of ovarian cancer patients before surgery, and after chemotherapy.The results indicated that ADA specific activity increased significantly (P<0.05), while 5 ́-NT and AMPDA specific activity decreased significantly (P<0.05) in ovarian cancer patients before surgery in comparison with those of their corresponding control women and benign tumors groups.When the activities of these enzymes were measured after chemotherapy, a significant decrease (P<0.05) in ADA activity, and a significant increase (P<0.05) in 5 ́-NT and AMPDA activities were found in comparison with those before surgery.
Article Type
Article
How to Cite this Article
Al-Shammaree, Shatha Abd AL- Wadood
(2010)
"Chemotherapy Effects on the Activities of Some Purine Metabolic Enzymes in Sera of Ovarian Cancer Patients,"
Baghdad Science Journal: Vol. 7:
Iss.
3, Article 12.
DOI: https://doi.org/10.21123/bsj.2010.7.3.1166-1173
