Abstract
This study is to evaluate plasma levels of several cytokines in preeclamptic pregnancies compared to those of healthy pregnancies.Ninety pregnant women with preeclampsia (37 mild & 53 severe) and thirty healthy pregnant women were enrolled in the study. Blood samples were taken and plasma levels of IL-8, IL-10, and IFN-γ were measured by enzyme-linked immunosorbent assay (ELISA).Preeclamptic women and their severe cases but not mild caseshad significantly(P<0.05)increased levels of plasma IL-8, and IFN-γ as compared with healthy pregnancies. By contrast, plasma levels of IL-10 was significantly (P<0.05) increased in healthy pregnant women as compared to all groups of preeclampsia.Preeclampsia is associated with an imbalance between pro-inflammatory cytokines (IL-8, IFN-γ) and anti-inflammatory cytokines (IL-10), and these support oursuggestion of altered immune response in preeclampsia
Article Type
Article
How to Cite this Article
Brakhas, Suaad A.; Jassim, Amna N; and Rahmah, Abbass M
(2011)
"Evaluation the levels of Plasma Interleukins (IL-8, IFN-γ, IL-10) in Preeclamptic Pregnancies,"
Baghdad Science Journal: Vol. 8:
Iss.
4, Article 8.
DOI: https://doi.org/10.21123/bsj.2011.8.4.918-925
