Abstract
Fifty one patients with serologically confirmed brucellosis and 70 healthy controls were phenotyped for HLA-A, -B, -DR and -DQ antigens by using standard microlympho-cytotoxicity method, and lymphocytes defined by their CD markers (CD3, CD4, CD8 and CD19). The results revealed a significant (Pc = 0.001) increased frequency of HLA-DR8 (41.18 vs. 10.0%) in the patients . A significant increased percentage of CD8+ lymphocytes was also increased in the patients (25.15 vs. 22.0%; P = 0.006), while CD3+ lymphocytes were significantly decreased (75.1 vs. 79.4%; P = 0.02).
Keywords
Brucellosis, HLA, CD markers
Article Type
Article
How to Cite this Article
Ad'hiah, Ali H.; Al-Rikaby, Aaiad H. A.; and Jasim, Ammna N.
(2012)
"Frequency of HLA Antigens in a Sample of Iraqi Brucellosis Patients,"
Baghdad Science Journal: Vol. 9:
Iss.
1, Article 12.
DOI: https://doi.org/10.21123/bsj.2012.9.1.86-92