Abstract
A sensitive spectrofluorimetric method for the determination of glibenclamide in its tablet formulations has been proposed. The method is based on the dissolving of glibenclamide in absolute ethanol and measuring the native fluorescence at 354 nm after excitation at 302 nm. Beers law is obeyed in the concentration of 1.4 to 10 µg.ml-1 of glibenclamide with a limit of detection (LD) of 0.067 µg.ml-1 and a standard deviation of 0.614. The range percent recoveries (N=3) is 94 - 103.
Keywords
Glibenclamide, spectrofluorimetric
Article Type
Article
How to Cite this Article
Khalaf, Karim D. and Hassen, Perween A.
(2012)
"Spectrofluorimetric method for the determination of glibenclamide in pharmaceutical formulations,"
Baghdad Science Journal: Vol. 9:
Iss.
2, Article 14.
DOI: https://doi.org/10.21123/bsj.2012.9.2.296-301
