SYNTHESIS,ANTIBACTERIAL ACTIVITY OF 2-AMINO 5-PHENYL -1,3,4- OXADIAZOLE DERIVATIVES

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Hussain jassem Mohammed

Abstract

In the present investigation, five derivatives were synthesized as potential  antimicrobial   agents , The compounds  are : 2-amino 5-phenyl - 1,3,4-  oxadiazole  dithi-ocarbomate, 2-amino 5-( 4-amino- N,N-dimethyl phenyl)-  1,3,4- oxadiazole,    2-amino 5- (4-amino N,N- dimethyl phenyl)- 1,3,4- oxadizole  dithiocarbamate, 2-amino 5-(4-nitr-ophenyl)-1,3,4-oxadiazole, 2-amino 5-(4-nirophenyl)-1,3,4- oxadiazole  dithiocarbamate.


The   above   newly  synthesized  compounds   were  investigated  for their  antibacterial, antifungal activities. The results of the biological revealed that the compounds  activities against S.aureuss and B.subtilis and also P.aeureoginosa and    Staph. Aureus. The    prepared   compounds were characterized by infrared spectrum, 1HNMR  nuclear magnetic resonance and some physical properties.                          

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SYNTHESIS,ANTIBACTERIAL ACTIVITY OF 2-AMINO 5-PHENYL -1,3,4- OXADIAZOLE DERIVATIVES. Baghdad Sci.J [Internet]. 2008 Dec. 7 [cited 2024 Dec. 4];5(4):646-51. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/11877
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How to Cite

1.
SYNTHESIS,ANTIBACTERIAL ACTIVITY OF 2-AMINO 5-PHENYL -1,3,4- OXADIAZOLE DERIVATIVES. Baghdad Sci.J [Internet]. 2008 Dec. 7 [cited 2024 Dec. 4];5(4):646-51. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/11877

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