Spectrophotometric determination of salbutamol sulphate in bulk and in pharmaceutical formulations

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Maha Kadhim Salman

Abstract

A new simple and sensitive colorimetric method has been developed for determination of salbutamol in aqueous solutions. The method is based on the formation of a yellow colored azo dye by diazotization of 2,4-dichloroaniline, followed by a azo-coupling reaction between the resulting product and salbutamol. The maximum absorbance  of azo dye at 447 nm. Beer's law was found to be obeyed in the concentration range of 2.5-20 μg/ml with range of molar absorptivity between(4000-7265) Lmol-1cm-1. The optimum reaction conditions and other analytical parameters were evaluated.

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Spectrophotometric determination of salbutamol sulphate in bulk and in pharmaceutical formulations. Baghdad Sci.J [Internet]. 2024 Oct. 7 [cited 2024 Nov. 6];7(1):1-8. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/11922
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How to Cite

1.
Spectrophotometric determination of salbutamol sulphate in bulk and in pharmaceutical formulations. Baghdad Sci.J [Internet]. 2024 Oct. 7 [cited 2024 Nov. 6];7(1):1-8. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/11922

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