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Fifty one patients with serologically confirmed brucellosis and 70 healthy controls were phenotyped for HLA-A, -B, -DR and -DQ antigens by using standard microlympho-cytotoxicity method, and lymphocytes defined by their CD markers (CD3, CD4, CD8 and CD19). The results revealed a significant (Pc = 0.001) increased frequency of HLA-DR8 (41.18 vs. 10.0%) in the patients . A significant increased percentage of CD8+ lymphocytes was also increased in the patients (25.15 vs. 22.0%; P = 0.006), while CD3+ lymphocytes were significantly decreased (75.1 vs. 79.4%; P = 0.02).
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Journal BS. Frequency of HLA Antigens in a Sample of Iraqi Brucellosis Patients: Ali H. Ad’hiah | Aaiad H. A. Al-Rikaby | Ammna N. Jasim. Baghdad Sci.J [Internet]. 2012Mar.4 [cited 2021Jul.28];9(1):86-92. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1337