Spectrofluorimetric method for the determination of glibenclamide in pharmaceutical formulations Karim D. Khalaf | Perween A. Hassen

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Baghdad Science Journal

Abstract

A sensitive spectrofluorimetric method for the determination of glibenclamide in its tablet formulations has been proposed. The method is based on the dissolving of glibenclamide in absolute ethanol and measuring the native fluorescence at 354 nm after excitation at 302 nm. Beers law is obeyed in the concentration of 1.4 to 10 µg.ml-1 of glibenclamide with a limit of detection (LD) of 0.067 µg.ml-1 and a standard deviation of 0.614. The range percent recoveries (N=3) is 94 - 103.

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How to Cite
1.
Journal BS. Spectrofluorimetric method for the determination of glibenclamide in pharmaceutical formulations: Karim D. Khalaf | Perween A. Hassen. Baghdad Sci.J [Internet]. 2012Jun.3 [cited 2021Jul.28];9(2):296-301. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1363
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