Spectrophotometric method for the determination of Captopril in pharmaceutical formulations Dawood H. Mohammed|Intesar A. Shehab|Hend Ahmed

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Baghdad Science Journal

Abstract

A simple, rapid and sensitive spectrophotometric method has been developed for the determination of captopril in aqueous solution. The method is based on reaction of captopril with 2,3-dichloro 1,4- naphthoquinon(Dichlone) in neutral medium to form a stable yellow colored product which shows maximum absorption at 347 nm with molar absorptivity of 5.6 ×103 L.mole-1. cm-1. The proposed method is applied successfully for determination of captopril in commercial pharmaceutical tablets.

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How to Cite
1.
Journal BS. Spectrophotometric method for the determination of Captopril in pharmaceutical formulations: Dawood H. Mohammed|Intesar A. Shehab|Hend Ahmed. Baghdad Sci.J [Internet]. 2013Sep.1 [cited 2021Aug.4];10(3):965-70. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2606
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