Synthesis of Some new 2-(4-Aryliminophenoxy)N-Arylacetamide Via p-hydroxy benzaldehyde. Ruwa M. Mauf|Asmaa H. Sultan|AmeeraM.Farag

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Baghdad Science Journal

Abstract

Chloroacetamide derivatives (2a-g) have been prepared through reaction of chloroacetyl chloride(1) (which prepared by the reaction of chloroacetic acid with thionyl chloride) with primary aromatic amines and sulfa compounds to afford compounds (2a-g) which then reacted with p-hydroxy benzaldehyde via Williamson reaction to obtaine the new compounds 2-(4-formyl phenoxy)-N-aryl acetamide (3a-g). Finally , compounds (3a-g) will be use as a good synthon to prepare the Schiff bases represented by compounds 2-(4-aryliminophenoxy)-N-arylacetamide (4a-g). through , reaction with some primary aromatic amine. All the prepared compounds were investigated by the available physical and spectroscopic methods.

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1.
Journal BS. Synthesis of Some new 2-(4-Aryliminophenoxy)N-Arylacetamide Via p-hydroxy benzaldehyde.: Ruwa M. Mauf|Asmaa H. Sultan|AmeeraM.Farag. Baghdad Sci.J [Internet]. 2014Jun.1 [cited 2021Aug.4];11(2):486-90. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2654
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