Spectrophotometric and Spectrofluorimetric Determination of Terazosin in Tablets by Eosin Y

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Simple, sensitive and accurate two methods were described for the determination of terazosin. The spectrophotometric method (A) is based on measuring the spectral absorption of the ion-pair complex formed between terazosin with eosin Y in the acetate buffer medium pH 3 at 545 nm. Method (B) is based on the quantitative quenching effect of terazosin on the native fluorescence of Eosin Y at the pH 3. The quenching of the fluorescence of Eosin Y was measured at 556 nm after excitation at 345 nm. The two methods obeyed Beer’s law over the concentration ranges of 0.1-8 and 0.05-7 µg/mL for method A and B respectively. Both methods succeeded in the determination of terazosin in its tablets


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Zeena Z., Maysam H. Spectrophotometric and Spectrofluorimetric Determination of Terazosin in Tablets by Eosin Y. Baghdad Sci.J [Internet]. 2021Mar.30 [cited 2022Jun.26];18(1(Suppl.):0775. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/4870


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