Synthesis and Characterization of Some New Pyrazole, Triazole, Oxadiazole, Thiazole, Thiadiazole Derivatives Bearing p-Toluenesulfonamide
DOI:
https://doi.org/10.21123/bsj.2024.8533Keywords:
Benzene sulfonamide, Oxadizole, pyrazole, Thiazole, Triazole.Abstract
A series of new heterocyclic derivatives A5-A15 have been synthesized using 4-(toluene-4-sulfinylamino)-benzoic acid ethyl ester A2 as a predecessor. This compound A2 was successfully used in synthesis of some new derivatives of oxadiazole, pyrazole, triazole, thiadiazole, thiazole and fused heterocyclic containing p-toluene sulfonamide moiety that supposed to have important biological activities. 1H-NMR, 13C-NMR and FT-IR spectroscopy were used to confirm the prepared compounds.
Received 05/02/2023,
Revised 06/02/2023,
Accepted 08/02/2023,
Published Online First 20/03/2024
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