Synthesis and Characterization of New Acrylamide Derivatives and Studying Their Antibacterial Activity
DOI:
https://doi.org/10.21123/bsj.2024.8556Keywords:
Acrylamide, Antibacterial activity, Heterocyclic compounds, Oxazepine, Schiff s bases.Abstract
This study aims to test the new derivatives of polymers on the biological activities of two types of bacteria work describes the synthesis of 1,3-oxazepine and self-polymerization via a cycloaddition reaction between Schiff’s bases 2-methyl-N-(5-(2-methylbutanoylimino) pentylidene)but-2-enamide and succinic, maleic anhydride. The synthesized compounds were characterized by melting points, softening points, and physical properties such as swelling capacity, TGA, and FT-IR. The biological activity showed intermediate results against two bacterial isolates resistant to antibiotics.
Received 10/02/2023
Revised 08/09/2023
Accepted 10/09/2023
Published Online First 20/08/2024
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Copyright (c) 2024 Ruaa M. Dhedan , Sana H. Awaad , Suha. N. Fadhl
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