The Effect of Curcumin Powder and Cloves Oil on the Properties of Fibers Produced by Electrospinning Technology
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Abstract
Electrospinning is a simple method for obtaining nanofibers. They possess distinctive properties such as large surface area to weight and high porosity, which make them attractive for many applications. In this research, the electrospinning technique was used to obtain non-woven mats of fibers using polylactic acid (PLA) with the addition of curcumin powder and clove oil as natural antibacterial materials. For the preparation of mats, a 10% polylactic acid solution was prepared in a mixture of acetone and dimethylformamide. Natural materials were added to the polymer solution in several concentrations of 1, 3, 5, 7, and 10%. The viscosity of these solutions was measured. The samples were then prepared using a locally manufactured electro-spinner. Using a scanning electron microscope, it was found that the average diameter of the fibers of the polylactic acid sample is 177 nm. It is noted that the diameters of the fibers produced using polymer and natural materials have larger diameters, especially when curcumin is added, as the fiber diameters range between 485 and 764 nm. The activity of the produced samples against two types of Gram-negative and Gram-positive bacteria was tested. It was found that the polymer-only sample did not have any resistance to the bacteria. While samples containing natural materials showed antibacterial activity against both types of bacteria. It was noted that this activity increased with the increase in the concentration of the additive, which produced an increase in the diameter of the inhibition zone, which makes it suitable for medical and other applications.
Received 20/09/2023
Revised 28/11/2023
Accepted 30/11/2023
Published Online First 20/05/2024
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References
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