دراسة بعض عوامل الضراوة ومقاومة المضادات للبكتريا المعزولة من إدرار المرضى المصابين بسرطان المثانة

محتوى المقالة الرئيسي

Sura Mouaid Abbas
Maysaa Abdul Razzaq Dhahi

الملخص

التهاب المجاري البولية تعني وجود المكروبات الممرضة بالاحليل أو المثانة. أهم الأسباب لحدوث الأصابات المتكررة هو تخدش لمجرى البول نتيجة استعمال القسطرة البولية أو الأشخاص المكبوحين مناعيا. الدراسة الحالية ركزت على عزل وتشخيص المكروبات التي تسبب التهاب المجاري البولية ودراسة المقاومة الحيوية وبعض من عوامل الضراوة في الأشخاص المصابين بسرطان المثانة  Transcial cell carcinoma  نوع  واشخاص تنظير المثانة سلبي لهم.تم جمع 62 عينة ادرار (50 مرضى سرطان المثانة و12 اشخاص تنظير المثانة سلبي) فقط 32 عينة كانت موجبة لوجود البكتريا وكانت النسبة الاعلى بالاصابة هي uropathogenicEscherichia coli UPEC)) تليها Stenotrophomonasmaltophilia. نسبة العزلات المقاومة للمضادات الحيوية كانت (62.8%) MDR بينما XDR كانت(28.5%)  وكانت كل العزلات لها القابلية على انتاج الغشاء الحيوي اما بصورة متوسطة 17/35 (51%) او أنتاج قوي 17/35 (49%). أنتاج السيدروفور كان 25/35 (71%) منتجة و10/35 (29%) غير منتجة بينما قابلية لتحفيز لأنتاج السايتوكروم  P450 كان (14/35) 40% لها القابلية  و(21/35) 60% غير قادرة على الأنتاج.الاشخاص المصابين بسرطان المثانة اويخضعون لتنظير المثانة يكونوا عرضة للاصابة بالممرضات الانتهازية والعدوى من المستشفيات والتيمنال ممكنا نتطور المقاومة للمضادات الحيوية وهذه مشكلة اساسية لعلاج هذه الفئة من المرضى قبل اعطائهم العلاج الكيمياوي اوالمناعي .

تفاصيل المقالة

كيفية الاقتباس
1.
دراسة بعض عوامل الضراوة ومقاومة المضادات للبكتريا المعزولة من إدرار المرضى المصابين بسرطان المثانة. Baghdad Sci.J [انترنت]. 1 يونيو، 2022 [وثق 24 ديسمبر، 2024];19(3):0469. موجود في: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/5822
القسم
article

كيفية الاقتباس

1.
دراسة بعض عوامل الضراوة ومقاومة المضادات للبكتريا المعزولة من إدرار المرضى المصابين بسرطان المثانة. Baghdad Sci.J [انترنت]. 1 يونيو، 2022 [وثق 24 ديسمبر، 2024];19(3):0469. موجود في: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/5822

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