تحضير ودراسة خواص جسيمات الفضة النانوية و تطبيقاتها الطبية ضد البكتريا المرضية
محتوى المقالة الرئيسي
الملخص
في هذه الدراسة تم تصنيع جسيمات الفضة النانوية (Ag NPs) الصلدة والجوفاء تم توصيف الجسيمات النانوية باستخدام المجهر الإلكتروني النافذ (TEM)، وجهد زيتا، والتحليل الطيفي للأشعة المرئية والفوق البنفسجية، و حيود الأشعة السينية (XRD). كشفت صورة TEM عن شكل الشبه الكروي لكل من جسيمات الفضة النانوية (Ag NPs) الصلدة والجوفاء. كشف قياس الشحنة السطحية أنه جسيمات الفضة النانوية الجوفاء (Hollow Ag NPs) لها شحنة سطحية تبلغ قيمتها 43- مللي فولت، بيمنا جسيمات الفضة النانوية الصلدة (Solid Ag NPs) لها شحنة سطحية تبلغ قيمتها 33- مللي فولت. أظهرت جسيمات الفضة النانوية الصلدة والجوفاء قمم امتصاص عند أطوال موجية 436 نانومتر و 412 نانومتر، على التوالي، وفقًا لقياس التحليل الطيفي للأشعة فوق البنفسجية. اضهرت نتائج حيود الاشعة السينية أن التركيب البلوري للعينات مكعب وبأحجام جسيمات تبلغ حوالي 28 نانومتر و 27 نانومتر لجسيمات الفضة النانوية الصلدة والجوفاء، على التوالي. تم اختبار النشاط المضاد للميكروبات من Ag NPs المحضر على بعض السلالات البكتيرية الممرضة التي تم عزلها من مرضى التهاب المسالك البولية (UTI).والحروق , أظهرت نتائج التجربة فعالية إيجابية مبيده للجراثيم ضد البكتيريا المعزولة وكانت جسيمات الفضة النانوية الصلدة أكثر فاعلية ضد بكتيريا G-ve و G + ve. بالاضافة الى ان النشاط المضاد للميكروبات للجسيمات النانوية الصلدة كان معتمد على الوقت و التركيز.
Received 14/9/2022,
Revised 26/11/2022,
Accepted 27/11/2022,
Published Online First 20/5/2023
تفاصيل المقالة
هذا العمل مرخص بموجب Creative Commons Attribution 4.0 International License.
كيفية الاقتباس
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