IGFBP7علامة تشخيصية جديدة في امصال المرضى العراقيين المصابين بتضخم الأطراف
محتوى المقالة الرئيسي
الملخص
كان الغرض من هذه الدراسة هو قياس مستويات مصل البروتين المرتبط بعامل النمو الشبيه بالأنسولين (IGFBP7) ، وعامل النمو الشبيه بالأنسولين 1 (IGF-1) ، وهرمون النمو (GH) ، والإنترلوكين 6 (IL-6) والأنسولين. في مرضى تضخم الاطراف والاصحاء . مجموعة المرضى تكونت من 60 مريضًا ، بينما مجموعة الاصحاء تكونت من 30 شخصًا سليما. تم تحديد تركيز IGFBP7 و IGF-1 و GH و IL-6 والأنسولين. تشير نتائج الدراسة الحالية إلى أن مستوى IGFBP7 في مجموعة المرضى كان أقل بشكل ملحوظ (1.690.07 نانوغرام / مل) مقابل 2.740.12 نانوغرام / مل ، على التوالي ، p = 0.001) . كانت تراكيز IGF-1 و GH و IL-6 والأنسولين أعلى بشكل ملحوظ في مرضى تضخم الاطراف ، وكانت الدقة التشخيصية (2.194) ممتازة في فصل ضخامة النهايات عن مجموعة المرضى الأصحاء ، والمنطقة الواقعة تحت المنحنى (AUC = 0.871، p = 0.001). من نتائج الدراسة الحالية يمكننا أن نستنتج أن مصل IGFBP7 يمكن استخدامه لتمييز بين مرضى تضخم الاطراف عن الأفراد الأصحاء.
Received 18/09/2022
Revised 01/11/2022
Accepted 03/11/2022
Published 20/06/2023
تفاصيل المقالة
هذا العمل مرخص بموجب Creative Commons Attribution 4.0 International License.
كيفية الاقتباس
المراجع
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