The Effect of Sodium Selenite on Fertility of Albino Male Mice Treated with Hexavalent Chromium

Abstract

  This study was conducted to determine the effect of sodium selenite (0.5 mg/kg ) on fertility of mature albino mice treated with hexavalent chromium (1000 ppm) . 32 mice were divided into four groups : control group / group exposed to hexavalent chromium (1000 ppm) / group treated with sodium selenite (0.5 mg/kg) and exposed to hexavalent chromium (1000 ppm) / group treated with sodium selenite (0.5 mg/kg) alone . The experiment lasted for 35 day . The results showed a significant (P < 0.05) decrease in sperm motility , concentration , percentage of live sperm and testosterone concentration with a significant (P < 0.05) increase in the percentage of abnormal  sperm in group treated with hexavalent chromium in comparison with control group . The results also showed a significant (P < 0.05) increase in sperm motility , concentration , percentage of live sperm and testosterone concentration with a significant (P < 0.05) decrease in the percentage of abnormal sperm in group treated with Sodium selenite and exposed to hexavalent chromium in comparison with group exposed to  hexavalent chromium . The group treated with Sodium selenite alone showed an improvement in all parameters studied except the percentage of abnormal sperms which showed a significant (P < 0.05) decrease .