Synthesis, characterization and bioactivity Study from azo – ligand derived frommethyl-2-amino benzoatewith some metal ions
DOI:
https://doi.org/10.21123/bsj.2022.6584Keywords:
Bioactivity, complexes, ethanol, Molar conductivity, Transition MetalsAbstract
A Ligand (ECA) methyl 2-((1-cyano-2-ethoxy-2-oxoethyl)diazenyl)benzoate with metals of (Co2+, Ni2+, Cu2+) were prepared and characterization using H-NMR, atomic absorption spectroscopy, ultra violet (UV) visible, magnetic moments measurements, bioactivity, and Molar conductivity measurements in soluble ethanol. Complexes have been prepared using a general formula which was suggested as [M (ECA)2] Cl2, where M = (Cobalt(II), Nickel(II) and Copper(II), the geometry shape of the complexes is octahedral.
Received 28/9/2021
Accepted 28/2/2022
Published Online First 20/7/2022
References
Geersing A, Ségaud N, Monique G P, Van der Wijst
M G, Rots M G , Roelfes G, Importance of metalion exchange for the biological activity of
coordination complexes of the biomimetic ligand
N4Py. Inorg.Chem. 2018; 57(13), 7748-7756.
Yousif Q I, Alia F M ,Synthesis,Strctural study
Antimicrobial activity and theoretical treatment of
d-metal complexes involiving schuff base of
piperonal derivative AJPS. 2018;13(1):1-13
Sodhi R K, Paul S , Metal Complexes in Medicine an
Overview and Update from Drug Design
Perspective. Cancer Ther Oncol Int J. 2019; 14(1),
-32.
Karwan O A, Hikmat A M, Synthesis,
Characterization, and Antibacterial Activity of Ni(II),
Pd(II), and Pt(II) Complexes with 2-
benzoylthiobenzimidazole. Zanco J Pure Appl .2020;
(2): 15-23.
Ana A B, Supramolecular Assembly of Benzimidazole
Derivatives and Applications., DOI:
5772/intechopen . 2019; 85333 (Review).
Husain A, Varshney M, Rashid M , Akhter A,
benzimidazole : A Valuable Insight into the recent
Advances and Biological Activities J.Pharm Rese.
; 4(2) ,413-419.
Waleed A , Israa H , Synthesis and Spectral Analysis
of Mn(II), Cu(II) Ni (II) and Cd(II) Complexes with
Mixed Ligand containing 1,10- phenanthroline and
Schiff base derived of 4- aminoantipyrine. Baghdad
Sci J . 2014 ; 11(4): 1519-1521.
Hawraa M, Maha AL-T , Israa H,Muna S , Surfactant
Cloud Point Extraction as a Procedure of
Preconcentrating for Metoclopramide Determination
Using Spectro Analytical Technique, Baghdad Sci J .
; 17(1): 57-65.
Mahasn F A , Doaa H M , 2015.Synthesis , Spectral
Study and Theoretical Treatment of Mixing
Benzimidazole Derivatives and Phenanthroline
Complexe.ANJS.2016;19 :6056-6068.
A-Hammdani A, Al –Zoubi W,New metal complexes
N3 tridentate ligand Synthesis ,spectral studies and
biological activity .Spectrochim Acta A Mol Biomol
Spectrosc. 2016; 137: 75-89.
Anamm M, Sinan M, Rehab A, Muna A,
Synthesizing Structure and Characterizing
Bioactivites of Cr (III), La(III) and Ce(III)Complexes
with Nitrogen ,Oxygen and Sulpher donor bidentate
Schiff base ligands. Baghdad Sci.J. 2021; 18 (4)
Devi O,Basavaiah K, Vinay K, Revanasiddappa H,
Sensitive spectrophotometric determination of
metoclopramide hydrochloric in dosage forms and
spiked human urine using vanilline .Arab J Chem.
; 9: S64-S72.
Sahar S H, Nidhal M H , Shaymaa RB, Asmaa MS ,
Biological Evalution and Therotical Studay of Bidentate Ligand for Amoxicilline Derivative with
Some Metal Ions .Baghdad Sci.J. 2021; 18 (4)1269.
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