A New Green Approach of CFIA Technique for Direct Assay with a High Throughput of Sulfamethoxazole Drugs Using Condensation Reaction with NQS Agent

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Wasan A. Hanooan
Bushra B. Qassim

Abstract

A new design of manifold flow injection (FI) coupling with a merging zone technique was studied for sulfamethoxazole determination spectrophotometrically. The semiautomated FI method has many advantages such as being fast, simple, highly accurate, economical with high throughput . The suggested method based on the production of the orange- colored compound of SMZ with (NQS)1,2-Naphthoquinone-4-Sulphonic acid Sodium salt in alkaline media NaOH at λmax 496nm.The linearity range of sulfamethoxazole was  3-100  μg. mL-1, with (LOD) was 0.593 μg. mL-1 and the RSD% is about 1.25 and the recovery is 100.73%. All various physical and chemical parameters that have an effect on the stability and development of the colored product were accurately studied and the designed systems have been completely implemented successfully for sulfamethoxazole quantity estimation in pharmaceutical formulations and biological samples.

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Hanooan WA, Qassim BB. A New Green Approach of CFIA Technique for Direct Assay with a High Throughput of Sulfamethoxazole Drugs Using Condensation Reaction with NQS Agent. Baghdad Sci.J [Internet]. 2024 Feb. 1 [cited 2024 Feb. 22];21(2):0369. Available from: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/8104
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References

Alsahib SA. Characterization and Biological Activity of Some New Derivatives Derived from Sulfamethoxazole Compound. Baghdad Sci J .2020; 17(2): 0471. http://dx.doi.org/10.21123/bsj.2020.17.2.0471

Zhang W, Li R, Zhu M, Zhou W, Lai M, Liang H, Ye H. Ultrasensitive and indirect electrochemical detection of sulfamethoxazole using Ag2O@ MWCNTs Nanocomposites Modified Glassy Carbon Electrode. Int J Electrochem Sci. 2020; 15: 7610-7623. http://dx.doi.org/10.20964/2020.08.74

Minglu M, Yiyun C, Zhenhua X. Evaluation of polyamidoamine (PAMAM) dendrimers as drug carriers of anti2bacterial drugs using sulfamethoxazole (SMZ) as a model drug. Eur J Med Chem. 2007; 42(1): 93-98. http://dx.doi.org/10.1016/j.ejmech.2006.07.015

Fan J, Chen Y, Feng S, Ye C, Wang J. Flow-injection spectrophotometric determination of sulfadiazine and sulfamethoxazole in pharmaceuticals and urine. Anal Sci. 2003;19(3): 419-422. https://doi.org/10.2116/analsci.19.4199-422.

Ismaeel, Y Q, Al-Phalahy B A. A new cyproheptadine PVC ion selective electrode and their applications in pharmaceutical preparations and human fluid. Al-Nahrain J Sci. 2020; 23(2): 26-32. http://dx.doi.org/10.22401/ANJS.23.2.04

Saleem, F, Khan N, Ali I. Synthesis of hydroxamic ligands with transition metal complexes, their biological activities and characterization through spectroscopic techniques . Al-Nahrain J Sci. 2020; 23(2): 1-7. http://dx.doi.org/10.22401/ANJS.23.2.01

Sallal TD, Abass SM. Oxidative Coupling Reaction for Micro Trace Analysis of Mebendazol Residual with p-bromoaniline in Presence of n-bromosuccinimide. Baghdad Sci J. 2020; 17(3): 0780-0780. http://dx.doi.org/10.21123/bsj.2020.17.3.0780.

Abbas SM, Dawood FA, Muhammed Z. Spectrophotometric determination of sulfamethoxazole in pure and pharmaceutical formulations. J Appl spectrosc. 2021; 88(2): 1-8.

Gurumurthy T, Monika M, Ashwini V. Development and validation RPHPLC method for simultaneous estimation of sulfamethoxazole and trimethoprim. Indian J Biotech Pharm Res. 2017; 5(3): 235-8. https://doi.org/10.15446/rcciquifa.v51n1.95974

Patyra E, Przeniosło-Siwczyńska M, Kwiatek K. Determination of sulfonamides in feeds by high-performance liquid chromatography after fluorescamine precolumn derivatization. Molecules. 2019; 24(3): 452. https://doi.org/10.3390/molecules24030452

Pamreddy A, Hidalgo M, Havel J, Salvadó V. Determination of antibiotics (tetracyclines and sulfonamides) in biosolids by pressurized liquid extraction and liquid chromatography–tandem mass spectrometry. J Chromatogr A. 2013; 12(98): 68-75. https://doi.org/10.1016/j.chroma.2013.05.014.

Asadi S, Gharbani P. simultaneous Determination of Sulfamethoxazole and Phthalazine by HPLC and Multivariate Calibration MethodS. Iran J Chem Chem Eng. 2013; 32(2): 1-8.

Pietron W, Cybulski W,Krasucka D, Mitura A, Kos K, Antczak M. Determination of five sulfonamides in medicated feeding stuffs by liquid chromatography with ultraviolet detection. Bull Vet Inst Pulawy . 2013; 57(4): 545-552. http://dx.doi.org/10.2478/bvip-2013-0094

Hererra-Hererra A, V Hernández-Borges J, Borges-Miquel TM, Rodríguez- Delgado M Á. Dispersive liquid–liquid micro extraction combined with ultrahigh performance liquid chromatography for the simultaneous determination of 25 sulfonamide and quinolone antibiotics in water samples. J Pharma Biomed Anal. 2013; 75: 130-137. https://doi.org/10.1016/j.jpba.2012.11.026

Turco A, Corvaglia S, Mazzotta E, Pompa PP, Malitesta C. Preparation and characterization of molecularly imprinted mussel inspired film as antifouling and selective layer for electrochemical detection of sulfamethoxazole. Sens Actuators B: Chem. 2018; 255: 3374-3383. https://doi.org/10.1016/j.snb.2017.09.164

Wang HL, Si XJ, Wu TH, Wang P. New Enhanced Method for Determination of Trace Sulfamethodxazole Based on the Fluorescence Behaviors of Cyclodextrins in Water Solutions. J Fluoresc .2020; 30(5): 1105-1112. https://doi.org/10.1007/s10895-020-02582-3

Hamed LL, Qassim BB. Direct and new flow injection method for assay of Iron as ferrous sulfate in pure and dosage forms through the complexation with 2, 2︡ dipyridyl reagent. Int J Pharm Res. 2020; 12(2): 1329-1338. https://doi.org/10.31838/ijpr/2020.SP2.128

Qassim BB, Hamed LL. Simple green method high throughput flow injection technique for spectrophotometry determination of Fe (III) in Iron drugs through the reaction between DPA-4-Sulfonat with hydrogen peroxide using a modified detection unit. Int J Drug Deliv Technol. 2020; 10(4): 563-570. http://dx.doi.org/10.25258/ijddt.10.4.10

Fahad AS, Thani MZ, Abdullah AM, Dhahir SA. Development of an Ecological-friendly Method for Ciprofloxacin Determination and Cloud Point Extraction in Pharmaceuticals using Fe (II)(FeSO4. 7H2O). In IOP Conf Ser Mater Sci Eng. 2020; 871: 1-8 http://dx.doi.org/10.1088/1757-899X/871/1/012028.

Kadhim EA, Dhahir SA, Sando MS. New Diaz Coupling Reaction, Cloud Point Extraction Spectrophotometric Determination of Sulphadimidine Soudium in Pure form and Pharmacetical Preparation with Salicylic Acid as the Coupling Reaction. Indian J Forensic Med Toxico .2020; 14(2): 862-868. https://doi.org/10.37506/ijfmt.v14i2.2989.

Turkey NS, Jeber JN. Flow Injection Analysis with Turbidity Detection for the Quantitative Determination of Mebeverine Hydrochloride in Pharmaceutical Formulations. Baghdad Sci J .2022; 19(1): 0141. https://doi.org/10.21123/bsj.2022.19.1.0141.

Tzanavaras PD, Themelis DG, Economou A, Theodoridis G. Flow and sequential injection manifolds for the spectrophotometric determination of captopril based on its oxidation by Fe (III). Microchimica Acta. 2003; 142: 155-62. https://doi.org/10.1007/s00604-003-0952-x.