طريقة خضراء جديدة لتقنية التحليل الحقن الجرياني المستمر للتقدير المباشر مع نمذجة عالية للمجموعة الفعالة في السفوناميد في ادوية السلفاميثوكسازول باستخدام تفاعل التكثيف مع كاشف 2,1- نفثوكوينون-4- حامض سلفونيك
محتوى المقالة الرئيسي
الملخص
تمت دراسة التصميم الجديد لمنظومة الحقن الجرياني المتشعب المقترنة مع تقنية اندماج المناطق المتلاقية لتحديد سلفاميثاكسازول بطريقة طيفية تتميز طريقةالحقن الجرياني الشبه المؤتمت باالعديد من المزايا مثل السرعة , البساطة, الدقة العالية ,اقتصادية مع نمذجة عالية. الطريقة المقترحة تعتمد على تكوين مركب برتقالي داكن الون مع كاشف كاشف 2,1- نفثوكوينون-4- حامض سلفونيك في الوسط القاعدي من هيدروكسيد الصوديوم عند طول موجي 496 نانومتر كانت مديات الخطية للسلفاميثوكسازول 3-100 مايكروغرام .مل-1 -مع حدود كشف0.593 مايكروغرام.مل-1والانحراف المعياري النسبي حوالي 1.25 وكانت النسبة المئوية للأسترداد ٪100.73 تم دراسة جميع الظروف الفيزيائية والكيميائية بدقة التي لها تأثير على استقرارية الناتج الملون , تم تنفيذ الانظمة المصممة بالكامل لتقدير كمية السلفا في المستحضرات الصيدلانية والعينات البايولوجية.
Received 13/11/2022
Revised 10/02/2023
Accepted 12/02/2023
Published Online First 20/07/2023
تفاصيل المقالة
هذا العمل مرخص بموجب Creative Commons Attribution 4.0 International License.
كيفية الاقتباس
المراجع
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