Synthesis of Some New Hydrazide-Hydrazone and Heterocyclic Compounds Thiophene, Imine, Coumarin and Pyrazole Derivatives
DOI:
https://doi.org/10.21123/bsj.2024.9395Keywords:
Coumarin, Heterocyclic Compounds, Hydrazide-Hydrazone, Imine, Pyrazole, Thiophene.Abstract
A series of new thiophene, imine, coumarin and pyrazole derivatives X4-X16 were synthesized from N-(1-(4-(benzylsulfonyl)phenyl)ethylidene)-2-cyanoacetohydrazide X3 as a starting material with different reagents (tetralone, cyclopentanone, cycloheptanone, 2-hydroybenzaldehyde, 2-hydroxy-1-naphthaldehyde, CS2 and phenylisothiocyanate). The compound X3 was synthesized by the reaction of 4-(benzylsulfonyl)acetophenone with 2-cyanoacetohydrazide under reflux in ethanol. The structures of all synthesized compounds were confirmed by (FT-IR, 1H-NMR, and 13C-NMR).
Received 11/09/2023
Revised 22/12/2023
Accepted 24/12/2023
Published Online First 20/08/2024
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