Synthesis, Characterization and Studying Thermal Analysis for Complexes of Some Metal Ions and Determining Their Activity as Antioxidants
DOI:
https://doi.org/10.21123/bsj.2024.9644Keywords:
Antioxidant, Azo complexes, 4-aminoethyl-cyclohexanecarboxylic, Mass spectra, Thermal analysis.Abstract
According to previous studies, a new azo ligand (N-(3-acetyl-2-hydroxy-5-methyl-phenyl)N-(4-carboxy-cyclohexylmethyl)-diazonium salt) was prepared and after verifying the proposed formula according to the results of the analyzes and after using Ligand to prepare a series of complexes using equal molar ratios (1:1) of the ligand and its reaction with each of the salts of manganese, cobalt, nickel, copper and zinc, and after verification according to spectroscopic (ultraviolet and infrared) and diagnostic analysis techniques, which gave tetrahedral shapes for all complexes in a neutral formula, and the ligand is tridentate (NOO) related to azo, ketonic and phenolic hydroxyl group, respectively .Then, the thermal decomposition of some compounds prepared using the TGA and DSC was studied and mass spectroscopy. The dye of the complexes prepared from it was used to determine their ability to inhibit free radicals by measuring their ability as antioxidants using DPPH as a free radical and ascorbic acid as a standard substance, and determining the IC50 value, as it was found that the ligand has a high ability to inhibit free radicals, and the complexes’ ability to inhibit it varied according to the IC50 value. The results were as following (Ascorbic acid(0.022) < LH(0.124) < Zn-complex(0.186) < Mn-complex(0.316) < Co-complex(0.635) <Cu-complex(2.234) <Ni-complex(2.351)) and showed its ineffectiveness in inhibiting the growth of bacteria or fungi according to the concentrations prepared.
Received 24/09/2023
Revised 18/03/2024
Accepted 20/03/2024
Published Online First 20/10/2024
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Copyright (c) 2024 Rasha Khider Hussain Al-Daffay, Abbas Ali Salih Al-Hamdani , Emran Abduljabbar Emran Elluhaibi
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