تحضير وتشخيص ودراسة تحلل حراري لمعقدات بعض ايونات المعادن وتقييم فعاليتها كمضادات اكسدة
DOI:
https://doi.org/10.21123/bsj.2024.9644الكلمات المفتاحية:
مضادات اكسدة ،معقدات الازو ،4-امينو مثيل-سايكلوهكسان كاربوكسيلك، اطياف الكتلة ، التحاليل الحراريةالملخص
وفقأ للدراسات السابقة تم تحضير ليكاند آزو جديد (ن-(3-اسيتايل-2-هيدروكسي-5-مثيل-فنيل)ن-(4-كاربوكسي-سايكلوهكسيل مثيل)-ملح الدايازونيوم) وبعد التحقق من الصيغة المقترحة وفق نتائج التحاليل وبعد استخدام الليكاند لتحضير سلسلة ن المعقدات باستخدام نسب مولية متساوية (1:1) من الليكاند وتفاعلها مع كل من املاح المنغنيز والكوبلت والنيكل والنحاس والخارصين وبعد التحقق وفق تقنيات التحاليل الطيفية والتشخيصية(الاشعة فوق البنفسية والاشعة تحت الحمراء) التي اعطت اشكال رباعية السطوح لكل المعقدات بصيغة متعادلة والليكاند ثلاثي السن من نوع (نيتروجين- اوكسجين- اوكسجين) ثم دراسة التحلل الحراري لبعض المركبات المحضرة بتقنية التحليل الوزني الحراري و المسعر التفاضلي مطيافية الكتلة . استخدم الصبغة المعقدات المحضرة منها لتحدد قابليتها على كبح الجذور الحرة من خلال قياس قابليتها كمضادات اكسدة باستخدام مادة DPPHكجذر حر وحامض الاسكوربك كمادة قياسية وتحديد قيمة IC50 حيث وجد ان الليكاند يمتلك قابلية عالية على كبح الجذور الحرة والمعقدات تفاوتت قابليتها على الكبح حسب قيمة IC50وكانت النتائج كما يلي
Received 24/09/2023
Revised 18/03/2024
Accepted 20/03/2024
Published Online First 20/10/2024
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الحقوق الفكرية (c) 2024 Rasha Khider Hussain Al-Daffay, Abbas Ali Salih Al-Hamdani , Emran Abduljabbar Emran Elluhaibi
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