Evaluation the levels of Plasma Interleukins (IL-8, IFN-?, IL-10) in Preeclamptic Pregnancies

محتوى المقالة الرئيسي

Suaad A. Brakhas
Amna N Jassim
Abbass M Rahmah

الملخص

This study is to evaluate plasma levels of several cytokines in preeclamptic pregnancies compared to those of healthy pregnancies.
Ninety pregnant women with preeclampsia (37 mild & 53 severe) and thirty healthy pregnant women were enrolled in the study. Blood samples were taken and plasma levels of IL-8, IL-10, and IFN-? were measured by enzyme-linked immunosorbent assay (ELISA).
Preeclamptic women and their severe cases but not mild cases had significantly (P<0.05) increased levels of plasma IL-8, and IFN-? as compared with healthy pregnancies. By contrast, plasma levels of IL-10 was significantly (P<0.05) increased in healthy pregnant women as compared to all groups of preeclampsia. Preeclampsia is associated with an imbalance between pro-inflammatory cytokines (IL-8, IFN-?) and anti-inflammatory cytokines (IL-10), and these support our suggestion of altered immune response in preeclampsia.

تفاصيل المقالة

كيفية الاقتباس
1.
Evaluation the levels of Plasma Interleukins (IL-8, IFN-?, IL-10) in Preeclamptic Pregnancies. Baghdad Sci.J [انترنت]. 4 ديسمبر، 2011 [وثق 28 ديسمبر، 2024];8(4):918-25. موجود في: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1310
القسم
article

كيفية الاقتباس

1.
Evaluation the levels of Plasma Interleukins (IL-8, IFN-?, IL-10) in Preeclamptic Pregnancies. Baghdad Sci.J [انترنت]. 4 ديسمبر، 2011 [وثق 28 ديسمبر، 2024];8(4):918-25. موجود في: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1310
Crossref
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Leasly Sanjoita Lamma, Muh Nasrum Massi, Sitti Wahyuni, Prihantono, Yuyun Widaningsih (2021)
Preeclampsia and normotensive pregnancy with tribal differences in South Sulawesi: Comparison of serum interleukin-10 (IL-10) levels. Gaceta Sanitaria, 35, S314.

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