Evaluation the levels of Plasma Interleukins (IL-8, IFN-?, IL-10) in Preeclamptic Pregnancies
محتوى المقالة الرئيسي
الملخص
This study is to evaluate plasma levels of several cytokines in preeclamptic pregnancies compared to those of healthy pregnancies.
Ninety pregnant women with preeclampsia (37 mild & 53 severe) and thirty healthy pregnant women were enrolled in the study. Blood samples were taken and plasma levels of IL-8, IL-10, and IFN-? were measured by enzyme-linked immunosorbent assay (ELISA).
Preeclamptic women and their severe cases but not mild cases had significantly (P<0.05) increased levels of plasma IL-8, and IFN-? as compared with healthy pregnancies. By contrast, plasma levels of IL-10 was significantly (P<0.05) increased in healthy pregnant women as compared to all groups of preeclampsia. Preeclampsia is associated with an imbalance between pro-inflammatory cytokines (IL-8, IFN-?) and anti-inflammatory cytokines (IL-10), and these support our suggestion of altered immune response in preeclampsia.
Ninety pregnant women with preeclampsia (37 mild & 53 severe) and thirty healthy pregnant women were enrolled in the study. Blood samples were taken and plasma levels of IL-8, IL-10, and IFN-? were measured by enzyme-linked immunosorbent assay (ELISA).
Preeclamptic women and their severe cases but not mild cases had significantly (P<0.05) increased levels of plasma IL-8, and IFN-? as compared with healthy pregnancies. By contrast, plasma levels of IL-10 was significantly (P<0.05) increased in healthy pregnant women as compared to all groups of preeclampsia. Preeclampsia is associated with an imbalance between pro-inflammatory cytokines (IL-8, IFN-?) and anti-inflammatory cytokines (IL-10), and these support our suggestion of altered immune response in preeclampsia.
تفاصيل المقالة
كيفية الاقتباس
1.
Evaluation the levels of Plasma Interleukins (IL-8, IFN-?, IL-10) in Preeclamptic Pregnancies. Baghdad Sci.J [انترنت]. 4 ديسمبر، 2011 [وثق 28 ديسمبر، 2024];8(4):918-25. موجود في: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1310
القسم
article
كيفية الاقتباس
1.
Evaluation the levels of Plasma Interleukins (IL-8, IFN-?, IL-10) in Preeclamptic Pregnancies. Baghdad Sci.J [انترنت]. 4 ديسمبر، 2011 [وثق 28 ديسمبر، 2024];8(4):918-25. موجود في: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1310
(2021)
Preeclampsia and normotensive pregnancy with tribal differences in South Sulawesi: Comparison of serum interleukin-10 (IL-10) levels.
Gaceta Sanitaria, 35, S314.