Stationary Distribution of Stochastic SEIRS Epidemic Model with Saturated Incidence Rate and Saturated Treatment Function
DOI:
https://doi.org/10.21123/bsj.2024.11183Keywords:
Extinction, Lyapunov function, Mathematical modelling, Stationary distribution, Stochastic SEIRS epidemic modelAbstract
This investigation aims to enhance and broaden the mathematical model that governs a dynamic stochastic SEIRS (Susceptible, Exposed, Infective, and Recovery) epidemic. This complex model integrates crucial components, including a saturated incidence rate and saturated treatment function, which are fundamental in molding epidemic dynamics. The objective is to explore the presence and uniqueness of a positive global solution through the application of a meticulously designed Lyapunov function, facilitating a more profound analysis of the intricacies of the systems. This analytical framework enables us to uncover the interactions among disease transmission, treatment dynamics, and stochastic influences. This theoretical framework assumes that treatment responses are directly related to incidence cases within the healthcare system as long as they remain within the system. A key aspect of our contribution lies in defining the stochastic basic reproduction number as a critical threshold that determines the course of the epidemic. Under conditions characterized by low noise levels and , it establishes the prerequisites for the appearance of an ergodic stationary distribution, offering insights into the potential long-term trends in disease dissemination. Conversely, in scenarios characterized by high noise intensity , our analysis sheds light on the inevitable eradication of the disease. To further enhance the theoretical underpinning, our research integrates extensive numerical simulations. These simulations not only confirm the validity of our theoretical findings but also provide a dynamic visualization of the implications of the model. The dual methodology of theoretical analysis and simulations contributes to a nuanced understanding of stochasticity and epidemic dynamics.
Received 14/03/2024
Revised 24/06/2024
Accepted 26/06/2024
Published Online First 20/12/2024
References
Alshammari FS, Khan MA. Dynamic behaviors of a modified SIR model with nonlinear incidence and recovery rates. Alex Eng J. 2021 Jun 1; 60(3): 2997-3005. https://doi.org/10.1016/j.aej.2021.01.023.
Pan Q, Huang J, Wang H. An SIRS Model with Nonmonotone Incidence and Saturated Treatment in a Changing Environment. J Math Biol. 2022 Sep; 85(3): 1-39. https://doi.org/10.1007/s00285-022-01787-3.
Brauer F, Castillo-Chavez C. Mathematical Models in Population Biology and Epidemiology. 2nd edition. New York: Springer; 2012. 508 p. https://doi.org/10.1007/978-1-4614-1686-9.
Naji RK, Thirthar AA. Stability and Bifurcation of an SIS Epidemic Model with Saturated Incidence Rate and Treatment Function. Iran J Math Sci Inform. 2020 Oct 10; 15(2): 129-146. https://doi.org/10.29252/ijmsi.15.2.129 .
Lu Y, Wang W, Chen H, Yan Y, Zhou X. Study on the Dynamics of an SIR Epidemic Model with Saturated Growth Rate. J Appl Math Phys. 2022 Jul 11; 10(7): 2164-2174. https://doi.org/10.4236/jamp.2022.107148 .
Cao H, Gao X, Li J, Yan D, Yue Z. The Bifurcation Analysis of an SIRS Epidemic Model with Immunity Age and Constant Treatment. Appl Anal. 2021 Oct 3; 100(13): 2844-2866. https://doi.org/10.1080/00036811.2019.1698728
Sun D, Li Y, Teng Z, Zhang T, Lu J. Dynamical Properties in an SVEIR Epidemic Model with Age‐Dependent Vaccination, Latency, Infection, and Relapse. Math Methods Appl Sci. 2021 Nov 30; 44(17): 12810-12834. https://doi.org/10.1002/mma.7583.
Parsamanesh M, Erfanian M. Stability and Bifurcations in a Discrete-Time SIVS Model with Saturated Incidence Rate. Chaos Solit. Fractals. 2021 Sep 1; 150: 111178. https://doi.org/10.1016/j.chaos.2021.111178.
Fisher RA. The Genetical Theory of Natural Selection — A Complete Variorum Edition. Oxford: Oxford University Press; 2000. 356 p.
Wright S. Evolution in Mendelian Populations. Bltn Mathcal Biology. 1990 Jan; 52: 241-295. DOI: https://doi.org/10.1007/BF02459575.
Grubaugh ND, Petrone ME, Holmes EC. We Shouldn’t Worry When a Virus Mutates During Disease Outbreaks. Nat Microbiol. 2020; 5: 529-530. https://doi.org/10.1038/s41564-020-0690-4.
Layne SP, Monto AS, Taubenberger JK. Pandemic Influenza: An Inconvenient Mutation. Science. 2009 Mar 20; 323(5921): 1560-1561. https://doi.org/10.1126/science.323.5921.1560 .
Crump KS, Hoel DG. Mathematical Models for Estimating Mutation Rates in Cell Populations. Biometrika. 1974 Aug 1; 61(2): 237-252. https://doi.org/10.1093/biomet/61.2.237
Wang W, Ruan S. Bifurcations in an Epidemic Model with Constant Removal Rate of the Infectives. J Math Anal. Appl. 2004 Mar 15; 291(2): 775-793. https://doi.org/10.1016/j.jmaa.2003.11.043.
Wang W. Backward Bifurcation of an Epidemic Model with Treatment. Math Biosci. 2006 May 1; 201(1-2): 58-71.
Zhang X, Liu X. Backward bifurcation of an epidemic model with saturated treatment function. Journal of mathematical analysis and applications. 2008 Dec 1;348(1):433-43. https://doi.org/10.1016/j.jmaa.2008.07.042.
Majeed SN, Naji RK. An Analysis of a Partial Temporary Immunity SIR Epidemic Model with Nonlinear Treatment Rate. Baghdad Sci J. 2019 Jul 1; 16(3): 639-647. https://doi.org/10.21123/bsj.2019.16.3.0639.
Ghosh JK, Majumdar P, Ghosh U. Qualitative Analysis and Optimal Control of an SIR Model with Logistic Growth, Non-Monotonic Incidence and Saturated Treatment. Math Model Nat Phenom. 2021; 16: 1-26. https://doi.org/10.1051/mmnp/2021004.
Saha P, Mondal B, Ghosh U. Dynamical Behaviors of an Epidemic Model with Partial Immunity having Nonlinear Incidence and Saturated Treatment in Deterministic and Stochastic Environments. Chaos Solit Fractals. 2023 Sep 1; 174: 113775. https://doi.org/10.1016/j.chaos.2023.113775.
Rajasekar SP, Pitchaimani M. Ergodic Stationary Distribution and Extinction of a Stochastic SIRS Epidemic Model with Logistic Growth and Nonlinear Incidence. Appl Math Comput. 2020 Jul 15; 377: 125143. https://doi.org/10.1016/j.amc.2020.125143.
Abdullah TH, Alizadeh F, Abdullah BH. COVID-19 Diagnosis System Using SimpNet Deep Model. Baghdad Sci. J. 2022 Oct 1; 19(5): 1078-1089. https://doi.org/10.21123/bsj.2022.6074.
Parsons TL, Bolker BM, Dushoff J, Earn DJ. The Probability of Epidemic Burnout in the Stochastic SIR Model with Vital Dynamics. Proc Natl Acad Sci. 2024 Jan 30; 121(5): e2313708120. https://doi.org/10.1073/pnas.2313708120.
Marković M, Krstić M. On a Stochastic Generalized Delayed SIR Model with Vaccination and Treatment. Nonlinearity. 2023 Nov 10; 36(12): 7007-7024. https://doi.org/10.1088/1361-6544/ad08fb .
Zhang J, Jia J, Song X. Analysis of an SEIR Epidemic Model with Saturated Incidence and Saturated Treatment Function. Sci World J. 2014 Jan 1; 2014(1): 1-11. https://doi.org/10.1155/2014/910421.
Saha P, Ghosh U. Complex Dynamics and Control Analysis of an Epidemic Model with Non-Monotone Incidence and Saturated Treatment. Int J Dynam Control. 2023 Feb; 11(1): 301-323. https://doi.org/10.1007/s40435-022-00969-7.
Li D, Cui JA, Liu M, Liu S. The Evolutionary Dynamics of Stochastic Epidemic Model with Nonlinear Incidence Rate. Bull Math Biol. 2015 Sep; 77: 1705-1743. https://doi.org/10.1007/s11538-015-0101-9.
Lan G, Yuan S, Song B. The Impact of Hospital Resources and Environmental Perturbations to the Dynamics of SIRS Model. J Frank Inst. 2021 Mar 1; 358(4): 2405-2433. https://doi.org/10.1016/j.jfranklin.2021.01.015.
Zhou B, Han B, Jiang D. Ergodic Property, Extinction and Density Function of a Stochastic SIR Epidemic Model with Nonlinear Incidence and General Stochastic Perturbations. Chaos Solit Fractals. 2021 Nov 1; 152: 111338. https://doi.org/10.1016/j.chaos.2021.111338.
Zhao Y, Yuan S, Ma J. Survival and Stationary Distribution Analysis of a Stochastic Competitive Model of Three Species in a Polluted Environment. Bull Math Biol. 2015 Jul; 77: 1285-1326. https://doi.org/10.1007/s11538-015-0086-4.
Feng T, Zhou H, Qiu Z, Kang Y. Impacts of Demographic and Environmental Stochasticity on Population Dynamics with Cooperative Effects. Math Biosci. 2022 Nov 1; 353: 108910. https://doi.org/10.1016/j.mbs.2022.108910.
Zhang X, Liu X. Backward Bifurcation of an Epidemic Model with Saturated Treatment Function. J Math Anal Appl. 2008 Dec 1; 348(1): 433-443. https://doi.org/10.1016/j.jmaa.2008.07.042.
Mao X. Stochastic Differential Equations and Applications. 2nd edition. Woodhead Publishing; 2011. Chap 6, Stochastic Equations of Neutral Type; p. 201-234. https://doi.org/10.1533/9780857099402.201.
Mao X, Marion G, Renshaw E. Environmental Brownian Noise Suppresses Explosions in Population Dynamics. Stoch. Process. Their Appl. 2002 Jan 1; 97(1): 95-110. https://doi.org/10.1016/S0304-4149(01)00126-0.
Khasminskii R. Stochastic Stability of Differential Equations. 2nd edition. Springer Berlin, Heidelberg; 2011. 342 p. https://doi.org/10.1007/978-3-642-23280-0.
Zhao Y, Jiang D. The Threshold of a Stochastic SIS Epidemic Model with Vaccination. Appl. Math. Comput. 2014 Sep 15; 243: 718-727. https://doi.org/10.1016/j.amc.2014.05.124.
Gao S, Chen L, Nieto JJ, Torres A. Analysis of a Delayed Epidemic Model with Pulse Vaccination and Saturation Incidence. Vaccine. 2006 Aug 28; 24(35-36): 6037-6045. https://doi.org/10.1016/j.vaccine.2006.05.018.
Zhang S, Meng X, Wang X. Application of Stochastic Inequalities to Global Analysis of a Nonlinear Stochastic SIRS Epidemic Model with Saturated Treatment Function. Adv Differ Equ. 2018 Dec; 2018(1): 1-22. https://doi.org/10.1186/s13662-018-1508-z.
Kundu S, Jana D, Maitra S. Study of a Multi-Delayed SEIR Epidemic Model with Immunity Period and Treatment Function in Deterministic and Stochastic Environment. Differ Equ Dyn Syst. 2021; 32: 221-251. https://doi.org/10.1007/s12591-021-00568-6.
Zhang Y, Zhu J. Ergodic Stationary Distribution of a Stochastic Rumor Propagation Model with General Incidence Function. Chin Phys B. 2022 Jun 1; 31(6): 060202. https://doi.org/10.1088/1674-1056/ac48fa .
Downloads
Issue
Section
License
Copyright (c) 2024 Saravanan S, Monica C
This work is licensed under a Creative Commons Attribution 4.0 International License.