Chemotherapy Effects on the Activities of Some Purine Metabolic Enzymes in Sera of Ovarian Cancer Patients
محتوى المقالة الرئيسي
الملخص
Adenosine deaminase (ADA; Ec: 3.5.4.4), 5´- Nucleotidase (5´– NT; Ec: 3.1.3.5), and AMP – amino hydrolase (AMP – deaminase AMPDA; Ec: 3.5.4.6) activities were measured in sera of ovarian cancer patients before surgery, and after chemotherapy.
The results indicated that ADA specific activity increased significantly (P<0.05), while 5´-NT and AMPDA specific activity decreased significantly
(P<0.05) in ovarian cancer patients before surgery in comparison with those of their corresponding control women and benign tumors groups.
When the activities of these enzymes were measured after chemotherapy, a significant decrease (P<0.05) in ADA activity, and a significant increase (P<0.05) in 5´- NT and AMPDA activities were found in comparison with those before surgery.
The results indicated that ADA specific activity increased significantly (P<0.05), while 5´-NT and AMPDA specific activity decreased significantly
(P<0.05) in ovarian cancer patients before surgery in comparison with those of their corresponding control women and benign tumors groups.
When the activities of these enzymes were measured after chemotherapy, a significant decrease (P<0.05) in ADA activity, and a significant increase (P<0.05) in 5´- NT and AMPDA activities were found in comparison with those before surgery.
تفاصيل المقالة
كيفية الاقتباس
1.
Chemotherapy Effects on the Activities of Some Purine Metabolic Enzymes in Sera of Ovarian Cancer Patients. Baghdad Sci.J [انترنت]. 5 سبتمبر، 2010 [وثق 19 مايو، 2024];7(3):1166-73. موجود في: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1086
القسم
article
كيفية الاقتباس
1.
Chemotherapy Effects on the Activities of Some Purine Metabolic Enzymes in Sera of Ovarian Cancer Patients. Baghdad Sci.J [انترنت]. 5 سبتمبر، 2010 [وثق 19 مايو، 2024];7(3):1166-73. موجود في: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1086
