تحضير وتشخيص ودراسة مضادات الاكسدة لمعقدات ايونات بعض العناصرمع ازو 1-(6،4،2-ثلاثي هيدروكسي-3-(3-هيدروكسي فنيل) ثنائي زينيل) فنيل) ايثان-1-اون
محتوى المقالة الرئيسي
الملخص
اثناء تفاعل الديزنة تكونت صبغة أزو جديدة عن طريق تفاعل 3-امينوفينول مع 2,4,6-ثلاثي هيدروكسي اسيتوفينون . ثم تم تفاعل هذا الليكاند مع بعض ايونات العناصر الكروم والحديد الروديوم والروثينيوم بتكفؤهم الثلاثي والكوبلت الثنائي والموليبدينوم سداسي التكافؤ مكونة معقدات فلزية مختلفة بأشكال هندسية متعددة. تم ملاحظة تناسق مجموعة الازو مع ايونات العناصر من خلال ملاحظة ظهور حزم امتصاص الفلز مع النتروجين والاوكسجين بتقنية مطيافية الاشعة تحت الحمراءمشيرة إلى ارتباط النيتروجين والأكسجين مباشرة مع الفلز .تم تعيين الاوزان الجزيئية لليكاند ومعقداته بأستخدام مطيافية الكتلة وكذلك تم عمل تحليل للعناصر. تم قياس حزم امتصاص الاطياف الالكترونية لتحديد الشكل الهندسي للمعقدات , اضافة الى ذلك تم تحديد استقرارية المركبات من حيث احتواءها على جزيئات الماء من عدمه باستخدام تقنيتي المسح الحراري التفاضلي التحليل الحراري الوزني تم قياس تأثير المعقدات كمضادات اكسدة اتجاه 2,2-داي فينل بكريل هيدرازيل (DPPH) وهو عبارة عن جذر حر مستقر الذي يتم استخدامه لمعرفة فعالية كسح الجذور الحرة لنواع الاوكسجين النشطة ولوحظ التالي (H4L > Ascorbic acid > Mo-Complex > Fe-Complex > Cr-Complex > Rh-Complex > Ru-Complex) خلال ثلاثون دقيقة . اختبار DPPH قام باختزال الالكترون المنفرد لذرة النتروجين عن طريق استلام ذرة هيدروجين من المعقدات المضادة للكسدة لتكوين الهيدرازين المقابل . نتيجة الفحص تراوحت مابين قيم تثبيط لمركبات نشطة وغير نشطة تم ادراجها في البحث.
Received 19/11/2023
Revised 14/01/2024
Accepted 16/01/2024
Published Online First 20/05/2024
تفاصيل المقالة
هذا العمل مرخص بموجب Creative Commons Attribution 4.0 International License.
كيفية الاقتباس
المراجع
Mohammed H. Synthesis, identification, and biological study for some complexes of azo dye having theophylline. Sci World J. 2021 Jul 22; vol. 2021:9. https://doi.org/10.1155/2021/9943763
Mahmudov KT, Gurbanov AV, Aliyeva VA, Resnati G, Pombeiro AJ. Pnictogen bonding in coordination chemistry. Coord Chem Rev. 2020 Sep 1; 418: 213381.https://doi.org/10.1016/j.ccr.2020.213381
Hamza IS, Mahmmoud WA, Al-Hamdani AA, AhmedSD, Allaf AW, Al Zoubi W. Synthesis, characterization, and bioactivity of several metalcomplexes of(4-Amino-N-(5-methyl-isaxazol-3-yl)-benzenesulfonamide) .Inorg Chem Commun. 2022; 144: 109776.
El-Gammal OA, Mohamed FS, Rezk GN, El-Bindary AA. Synthesis, characterization, catalytic, DNA binding and antibacterial activities of Co (II), Ni (II) and Cu (II) complexes with new Schiff base ligand. J Mol Liq. 2021; 15(326): 115223.https://doi.org/10.1016/j.molliq.2020.115223
El-Gammal OA, El-Bindary AA, Mohamed FS, Rezk GN, El-Bindary MA. Synthesis, characterization, design, molecular docking, anti COVID-19 activity, DFT calculations of novel Schiff base with some transition metal complexes. J Mol Liq. 2022; 15(346): 117850.https://doi.org/10.1016/j.molliq.2021.117850
Khedr AM, El-Ghamry H, Kassem MA, Saad FA, El-Guesmi N. Novel series of nanosized mono-and homobi-nuclear metal complexes of sulfathiazole azo dye ligand: Synthesis, characterization, DNA-binding affinity, and anticancer activity. Inorg. Chem. Commun. 2019; 1(108): 107496.https://doi.org/10.1016/j.inoche.2019.107496
Al-Hassani RA. Synthesis, Characterization, Antimicrobial and Theoretical Studies of V (IV), Fe (III), Co (II), Ni (II), Cu (II), and Zn (II) Complexes with Bidentate (NN) Donar Azo Dye Ligand. Baghdad Science Journal. 2016 Dec 4;13(4):0793- https://doi.org/10.21123/bsj.2016.13.4.0793.
Kirthan BR, Prabhakara MC, Naik HB, Nayak PA, Naik EI. Synthesis, characterization, DNA interaction and anti-bacterial studies of Cu (ii), Co (ii) and Ni (ii) metal complexes containing azo-dye ligand. Chem Data Collect. 2020 Oct 1; 29: 100506. https://doi.org/10.1016/j.cdc.2020.100506
Turan N, Buldurun K, Adiguzel R, Aras A, Turkan F, Bursal E. Investigation of spectroscopic, thermal, and biological properties of FeII, CoII, ZnII, and RuII complexes derived from azo dye ligand. J Mol Struct. 2021 Nov 15; 1244: 130989. https://doi.org/10.1016/j.molstruc.2021.130989
Abdallah SM, Zayed MA, Mohamed GG. Synthesis and spectroscopic characterization of new tetradentate Schiff base and its coordination compounds of NOON donor atoms and their antibacterial and antifungal activity. Arab J Chem. 2010; 3(2): 103-13.https://doi.org/10.1016/j.arabjc.2010.02.006
Kumar DN, Garg BS. Synthesis and spectroscopic studies of complexes of zinc (II) with N2O2 donor groups. SAA. Spectrochim Acta - A: Mol Biomol. 2006; 64(1) Ma: 141-7.https://doi.org/10.1016/j.saa.2005.07.008
Sahar YJ, Mohammed HS. Synthesis and characterization some complexes of azo dye of pyrimidyniyl and evaluating their biological activity. QJPS. 2019; 24(3). https://doi.org/10.29350/jops.2019.24.3.970
Deghadi RG, Mahmoud WH, Mohamed GG. Metal complexes of tetradentate azo-dye ligand derived from 4, 4-oxydianiline: Preparation, structural investigation, biological evaluation and MOE studies. Appl Organomet Chem. 2020; 34(10): e5883. https://doi.org/10.1002/aoc.5883
Al Zoubi W, Ko YG. Self-assembly of hierarchical N-heterocycles-inorganic materials into three-dimensional structure for superior corrosion protection. J Chem Eng. 2019; 356: 850-6.https://doi.org/10.1016/j.cej.2018.09.089
Kareem MJ, Al-Hamdani AAS, Jirjees VY, Khan ME, Allaf AW, Al Zoubi W. Preparation, spectroscopic study of Schiff base derived from dopamine and metal Ni (II), Pd (II), and Pt (IV) complexes, and activity determination as antioxidants. J Phys Org Chem. 2021; 34(3): e4156. https://doi.org/10.1002/poc.4156
Hadi MA, Kareem IK. synthesis, Characterization and Spectral Studies of a new Azo-Schiff base Ligand Derived from 3, 4-diamino benzophenone and its Complexes with Selected Metal Ions. J Adv Sci. 2020; 1(1).https://royalliteglobal.com/rjas/article/view/251
Waheeb AS, Kyhoiesh HA, Salman AW, Al-Adilee KJ, Kadhim MM. Metal complexes of a new azo ligand 2-[2′-(5-nitrothiazolyl) azo]-4-methoxyphenol (NTAMP): Synthesis, spectral characterization, and theoretical calculation. Inorg. Chem. Commun. 2022; 138: 109267.https://doi.org/10.1016/j.inoche.2022.109267
Deswal Y, Asija S, Dubey A, Deswal L, Kumar D, Jindal DK, et al. Cobalt (II), nickel (II), copper (II) and zinc (II) complexes of thiadiazole based Schiff base ligands: Synthesis, structural characterization, DFT, antidiabetic and molecular docking studies. J Mol Struct. 2022 Apr 5; 1253: 132266. https://doi.org/10.1016/j.molstruc.2021.132266
Al-Khateeb ZT, Karam FF, Al-Adilee K. Synthesis and characterization of some metals complexes with new heterocyclic azo dye ligand 2- [2--(5-Nitro thiazolyl) azo]-4-methyl-5-nitro phenol and their biological activities. J Phys Conf Ser.2019; 1294(5): 052043. IOP Publishing. https://doi.org/10.1088/1742-6596/1294/5/052043
Jaber SA, Kyhoiesh HA, Jawad SH. Synthesis, characterization and biological activity studies of cadmium (II) complex derived from azo ligand 2-[2-(5-bromo Thiazolyl) azo]-5-dimethyl amino benzoic acid. J Phys Conf Ser. 2021; 1818(1): 012013. https://doi.org/10.1088/1742-6596/1818/1/012013
Dahi MA, Jarad AJ. Synthesis, characterization and biological evaluation of thiazolyl azo ligand complexes with some metal ions. J Phys Conf Ser. 2020; 1664(1): 012090. https://doi.org/10.1088/1742-6596/1664/1/012090
Mohamed MG, EL-Mahdy AF, Kotp MG, Kuo SW. Advances in porous organic polymers: Syntheses, structures, and diverse applications. Mater Adv. 2022; 3(2): 707-33. https://doi.org/10.1039/D1MA00771H
Alhakimi AN, Shakdofa MM, Saeed S, Shakdofa AM, Al-Fakeh MS, Abdu AM , et al. Transition Metal Complexes Derived from 2-hydroxy-4-(p-tolyldiazenyl) benzylidene)-2-(p-tolylamino) acetohydrazide Synthesis, Structural Characterization, and Biological Activities. J Korean Chem. Soc. 2021; 65(2): 93-105. https://doi.org/10.5012/jkcs.2021.65.2.93
Al-Hamdani AAS, Al-Alwany TAM, Mseer MA, Fadhel AM, Al-Khafaji YF. Synthesis, Characterization, Spectroscopic, Thermal and Biological Studies for New Complexes with N1, N2-bis (3-hydroxyphenyl) Oxalamide. Egypt J Chem. 2023; 66(4): 223-235. https://doi.org/10.21608/EJCHEM.2022.144403.6297
Kyhoiesh HA, Al-Adilee KJ. Synthesis, spectral characterization, antimicrobial evaluation studies and cytotoxic activity of some transition metal complexes with tridentate (N, N, O) donor azo dye ligand. Results Chem. 2021; 3: 100245.https://doi.org/10.1016/j.rechem.2021.100245
Al-Daffay RK, Al-Hamdani AA, Al Zoubi W. Synthesis, Characterization and Thermal Analysis of Cu (II), Co (II), Ru (III) and Rh (III) Complexes of a New Acidic Ligand. Ibn al-Haitham J Pure Appl Sci. 2023 Oct 20; 36(4): 321-37. https://doi.org/10.30526/36.4.3047
Jain S, Dongare K, Nallamothu B, Dora CP, Kushwah V, Katiyar SS then et al. Enhanced stability and oral bioavailability of erlotinib by solid self nano emulsifying drug delivery systems. Int J Pharm. 2022; 622: 121852.https://doi.org/10.1016/j.ijpharm.2022.121852
Asim N, Amin MH, Alghoul MA, Sulaiman SN, Razali H, Akhtaruzzaman M, et al. Developing of chemically treated waste biomass adsorbent for dye removal. J Nat Fibers. 2021 Jul 3; 18(7): 968-77.https://doi.org/10.1080/15440478.2019.1675214
Shaalan N. Preparation, Spectroscopy, Biological Activities and Thermodynamic Studies of New Complexes of Some Metal Ions with 2-[5-(2-Hydroxy-Phenyl)-1, 3, 4-Thiadiazol-2-Ylimino]-Methyl-Naphthalen-1-Ol]. Baghdad Sci J. 2022; 19(4): 0829-.http://dx.doi.org/10.21123/bsj.2022.19.4.0829
Abdulridah M Q, Al-Hamdani A A S, Hussen IA. Synthesis, Characterization and Antioxidant Activity of New Azo Ligand and Some Metal Complexes of Tryptamine Derivatives.Baghdad Sci. J. 2023; 20(3 suppl.): 1046-1063. https://doi.org/10.21123/bsj.2023.8227
Hasan M. Synthesis, Identification, and BiologicalStudy for Some Complexes of Azo Dye HavingTheophylline. Sci World J. 2021; 76(3): 1-9. https://doi.org/10.1155/2021/9943763
Al-Daffay R. Kh., Al-Hamdani A. A. S," Synthesis, Characterization, and Thermal Analysis of a New Acidicazo Ligand's Metal Complexes.Baghdad Sci. J.2023;20(1): 121-133. https://doi.org/10.21123/bsj.2022.6709
Al Zoubi W, Al-Hamdani AAS, Duraid Ahmed S, Basheer HM, Al-Luhaibi RS, Dib A. Synthesis, characterization, and antioxidant activities of imine compounds. J Phys Org Chem. 2019 Mar; 32(3): e3916. https://doi.org/10.1002/poc.3916