التقدير الطيفي الاني باستخدام المشتقة النسبية للباراسيتامول والكافايين والايبوبروفين في اشكالها ثلاثية المكونات

المؤلفون

  • Khalaf F. Alsamarrai قسم الكيمياء، كلية التربية، جامعة سامراء، سامراء، العراق https://orcid.org/0000-0001-7980-8640
  • Suham Tawfeq Ameen قسم تقنيات المختبرات الطبية، كلية التقنيات الصحية والطبية، جامعة اوروك، بغداد، العراق

DOI:

https://doi.org/10.21123/bsj.2022.6422

الكلمات المفتاحية:

الكافايين, الايبوبروفين, الباراسيتامول, مساحة القمة, المشتقة النسبية

الملخص

تم اقتراح طريقتين جديدتين و دقبقتبن و متوافقتين و اقتصاديتين للتقدير الطيفي لكل من الباراسيتامول و الايبويروفين و الكافايين. والطريقتان هما المشتقة النسبية الاولى و الثانية ثنائية المقسوم عليه. و قد اعطى كل من الباراسيتامول و الايبوبروفين و الكافايين قمم مفيدة في التقدير الكمي لكل منهما. و قد تم تقييم جميع انواع تقنيات التقدير للمكونات الثلاثة و هي ارتفاع القمة الى خط الاساس ومساحة القمة و قمة الى قمة بالاستناد الى ICH. كان التناسب خطيا لكلا الطريقتين ما بين 5 مكغم/مل كاقل تركيز و 50 مكغم/مل كأعلى تركيز للمكونات الثلاثة. كانت الاسترجاعية المئوية حوالي 100% و الانحراف المعياري النسبي كان اقل من 2.6%. طبقت الطريقة بنجاح في تقدير كل من الباراسيتامول و الايبوبروفين و الكافايين في مكوناتها الصيدلانية.

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التنزيلات

منشور

2022-12-01

إصدار

القسم

article

كيفية الاقتباس

1.
التقدير الطيفي الاني باستخدام المشتقة النسبية للباراسيتامول والكافايين والايبوبروفين في اشكالها ثلاثية المكونات. Baghdad Sci.J [انترنت]. 1 ديسمبر، 2022 [وثق 12 مايو، 2024];19(6):1276. موجود في: https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/6422

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